CAJ | 학술논문

目的：探讨不同孕周早发型重度子痫前期（EOSP）的妊娠结局。方法对我院收治58例EOSP患者的临床资料进行回顾性分析。结果不同孕周的EOSP孕妇年龄、产次没有显著性差异，但是孕妇入院时平均动脉压差异明显（P<0.05）。28周之前的EOSP患者均有并发症，平均保胎时间也只有（4.5±1.6）d，随后多通过剖宫产或利凡诺引产终止妊娠，活产儿中窒息率66.7%，围生儿病死率44.4%；但是满28周的EOSP患者期待治疗时间平均达到（12.4±3.2）d，17.5%（7/40）的孕妇没有明显并发症，围生儿病死率下降（15.0%，6/40），活产儿中窒息率14.3%（5/35）。结论孕周28周之前EOSP孕妇病情重、并发症多，期待治疗后围生儿病死率、窒息率较高；而28周后EOSP孕妇并发症较少，期待治疗时间较长，围生儿结局相对较好。
목적：탐토불동잉주조발형중도자간전기（EOSP）적임신결국。방법대아원수치58례EOSP환자적림상자료진행회고성분석。결과불동잉주적EOSP잉부년령、산차몰유현저성차이，단시잉부입원시평균동맥압차이명현（P<0.05）。28주지전적EOSP환자균유병발증，평균보태시간야지유（4.5±1.6）d，수후다통과부궁산혹리범낙인산종지임신，활산인중질식솔66.7%，위생인병사솔44.4%；단시만28주적EOSP환자기대치료시간평균체도（12.4±3.2）d，17.5%（7/40）적잉부몰유명현병발증，위생인병사솔하강（15.0%，6/40），활산인중질식솔14.3%（5/35）。결론잉주28주지전EOSP잉부병정중、병발증다，기대치료후위생인병사솔、질식솔교고；이28주후EOSP잉부병발증교소，기대치료시간교장，위생인결국상대교호。
Objective To investigate the pregnancy outcome of early onset severe pre eclampsia (EOSP) with different gestational weeks. Methods The clinical data of 58 patients with EOSP in the hospital were retrospectively analyzed. Results The age and parity between the EOSP of pregnant women with different gestational weeks had no significant difference, but the mean arterial pressure were significantly different (P<0.05). All EOSP before 28 weeks had complications,conservative treatment time was 4.5 ± 1.6d, and mainly terminated pregnancy by cesarean section or rivanol termination, the asphyxia rate of live births was 66.7%with 44.4%perinatal mortality rate;but for the EOSP full of 28 weeks, average expectant treatment time was 12.4 ± 3.2d, 17.5% (7/40) of pregnant women had no complications, and the perinatal mortality rate decreased significantly (15%, 6/40) with only 14.3% asphyxia rate (5/35).Conclusion EOSP before 28 weeks of gestational age has severe illness, complications, perinatal mortality and asphyxia rate is higher. However, EOSP after 28 weeks has less complication, and expectant treatment time is longer, the perinatal outcome is good.