CAJ | 학술논문

目的：探讨阵发性心房颤动的临床表现及应用酒石酸美托洛尔的治疗效果。方法：2012年5月-2013年10月收治阵发性心房颤动患者80例，对所有患者进行酒石酸美托洛尔治疗，3个月后，再次对患者进行Holter监测，观察心房颤动的变化情况，采用多元Logistic回归分析法，分析阵发性心房颤动症状的有无与临床特征之间的关系。结果：80例患者中，无症状房颤发作的患者44例，有症状房颤发作的患者36例。患者接受治疗后，36例有症状房颤患者中症状完全消失20例，其中12例窦性心律，另外8例无症状房颤；44例无症状房颤患者中，无症状房颤发作的患者20例。心房颤动的症状与患者的年龄、性别有关，年轻女性产生症状的几率比较大(P＜0.05)，与心室率及心率差值呈正比关系(P＜0.05)，与左房内径呈反比关系(P＜0.05)。结论：无症状的阵发性房颤患者的发生率较高。酒石酸美托洛尔对阵发性心房颤动有良好的疗效，不仅可以减少无症状房颤的发作，又可以减少房颤患者的症状，值得在临床上推广应用。
목적：탐토진발성심방전동적림상표현급응용주석산미탁락이적치료효과。방법：2012년5월-2013년10월수치진발성심방전동환자80례，대소유환자진행주석산미탁락이치료，3개월후，재차대환자진행Holter감측，관찰심방전동적변화정황，채용다원Logistic회귀분석법，분석진발성심방전동증상적유무여림상특정지간적관계。결과：80례환자중，무증상방전발작적환자44례，유증상방전발작적환자36례。환자접수치료후，36례유증상방전환자중증상완전소실20례，기중12례두성심률，령외8례무증상방전；44례무증상방전환자중，무증상방전발작적환자20례。심방전동적증상여환자적년령、성별유관，년경녀성산생증상적궤솔비교대(P＜0.05)，여심실솔급심솔차치정정비관계(P＜0.05)，여좌방내경정반비관계(P＜0.05)。결론：무증상적진발성방전환자적발생솔교고。주석산미탁락이대진발성심방전동유량호적료효，불부가이감소무증상방전적발작，우가이감소방전환자적증상，치득재림상상추엄응용。
Objective:To explore the clinical manifestation of paroxysmal atrial fibrillation and the treatment effect of application of betaloc.Methods:80 patients with paroxysmal atrial fibrillation were selected from May 2012 to October 2013.They were treated with betaloc.After 3 months,they underwent subsequent Holter monitoring to observe the change of atrial fibrillation,and we analyzed the relationship between with or without symptoms of paroxysmal atrial fibrillation and clinical characteristics with multivariate Logistic regression analysis.Results:In 80 cases,44 cases were asymptomatic atrial fibrillation;35 cases were paroxysmal symptoms with atrial fibrillation.After treatment,in 35 cases with symptomatic AF patients,symptoms were disappeared completely in 20 cases,including 12 cases in sinus rhythm,8 additional cases of asymptomatic atrial fibrillation;in 44 cases of asymptomatic patients with atrial fibrillation,20 cases were asymptomatic AF episodes.Atrial fibrillation symptoms were associated with the patients' age,gender.In young women,the risk with symptoms was relatively large(P<0.05).It was positive with the ventricular rate and heart rate difference(P<0.05).It was negative with left atrial diameter(P<0.05).Conclusion:The incidence of asymptomatic patients with paroxysmal AF is higher.Betaloc has good efficacy in the treatment of paroxysmal atrial fibrillation, which can not only reduce episodes of asymptomatic atrial fibrillation,and can reduce the symptoms of patients with atrial fibrillation,so it is worthy of clinical application.