中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
39期
6375-6380
,共6页
孙辉%臧学慧%高立华%谭永滔
孫輝%臧學慧%高立華%譚永滔
손휘%장학혜%고립화%담영도
生物材料%骨生物材料%跟骨骨折%Genex人工合成骨%骨移植%骨缺损
生物材料%骨生物材料%跟骨骨摺%Genex人工閤成骨%骨移植%骨缺損
생물재료%골생물재료%근골골절%Genex인공합성골%골이식%골결손
calcaneus%fractures,bone%bone transplantation
背景:目前对 SandersⅢ型、Ⅳ型骨折手术治疗恢复破坏的跟骨距下关节面和跟骨形态,以减少创伤性关节炎的发生已达成共识,而对于跟骨骨折术中是否植骨一直是个有争议性的问题。目的:观察Genex人工合成骨填充材料及锁定钢板治疗粉碎性跟骨骨折的临床疗效。方法:回顾性分析21例SandersⅢ型、Ⅳ型跟骨骨折患者的临床资料,其中男16例,女5例,年龄22-55岁,采用外侧“L”形入路,跟骨骨折复位后将调好成面团样的 Genex 人工骨粉填塞缺损区,再将外侧壁骨块复位,将预弯好的锁定钢板置入。随访观察骨折愈合情况、Bolher角及Maryland足部评分。结果与结论:21例患者均获随访,随访时间8-16个月,骨折均愈合,无移位、塌陷及排斥反应,人工骨粉约6个月被降解,1年后完全被吸收,并为新骨所取代;按Maryland足部评分优良率达86%,Bolher角从治疗前的(5.30±3.35)°恢复至末次随访后的(24.30±1.06)°。结果表明 Genex 人工骨粉是一种完全吸收、可塑性好、支撑力强的生物材料,能够充分填充骨缺损,便于骨折复位、诱导成骨、促进骨折愈合。
揹景:目前對 SandersⅢ型、Ⅳ型骨摺手術治療恢複破壞的跟骨距下關節麵和跟骨形態,以減少創傷性關節炎的髮生已達成共識,而對于跟骨骨摺術中是否植骨一直是箇有爭議性的問題。目的:觀察Genex人工閤成骨填充材料及鎖定鋼闆治療粉碎性跟骨骨摺的臨床療效。方法:迴顧性分析21例SandersⅢ型、Ⅳ型跟骨骨摺患者的臨床資料,其中男16例,女5例,年齡22-55歲,採用外側“L”形入路,跟骨骨摺複位後將調好成麵糰樣的 Genex 人工骨粉填塞缺損區,再將外側壁骨塊複位,將預彎好的鎖定鋼闆置入。隨訪觀察骨摺愈閤情況、Bolher角及Maryland足部評分。結果與結論:21例患者均穫隨訪,隨訪時間8-16箇月,骨摺均愈閤,無移位、塌陷及排斥反應,人工骨粉約6箇月被降解,1年後完全被吸收,併為新骨所取代;按Maryland足部評分優良率達86%,Bolher角從治療前的(5.30±3.35)°恢複至末次隨訪後的(24.30±1.06)°。結果錶明 Genex 人工骨粉是一種完全吸收、可塑性好、支撐力彊的生物材料,能夠充分填充骨缺損,便于骨摺複位、誘導成骨、促進骨摺愈閤。
배경:목전대 SandersⅢ형、Ⅳ형골절수술치료회복파배적근골거하관절면화근골형태,이감소창상성관절염적발생이체성공식,이대우근골골절술중시부식골일직시개유쟁의성적문제。목적:관찰Genex인공합성골전충재료급쇄정강판치료분쇄성근골골절적림상료효。방법:회고성분석21례SandersⅢ형、Ⅳ형근골골절환자적림상자료,기중남16례,녀5례,년령22-55세,채용외측“L”형입로,근골골절복위후장조호성면단양적 Genex 인공골분전새결손구,재장외측벽골괴복위,장예만호적쇄정강판치입。수방관찰골절유합정황、Bolher각급Maryland족부평분。결과여결론:21례환자균획수방,수방시간8-16개월,골절균유합,무이위、탑함급배척반응,인공골분약6개월피강해,1년후완전피흡수,병위신골소취대;안Maryland족부평분우량솔체86%,Bolher각종치료전적(5.30±3.35)°회복지말차수방후적(24.30±1.06)°。결과표명 Genex 인공골분시일충완전흡수、가소성호、지탱력강적생물재료,능구충분전충골결손,편우골절복위、유도성골、촉진골절유합。
BACKGROUND:Currently, surgical treatment for Sanders III type, IV type fractures to restore damaged subtalar surface of the calcaneus and calcaneal shape, in order to reduce the incidence of traumatic arthritis has reached a consensus, and whether bone grafting is selected during surgery for calcaneal fractures has been a controversial issue. OBJECTIVE:To observe the clinical effect of Genex synthetic bone transplants and locking plate on comminuted calcaneal fractures. METHODS:Twenty-one cases of Sanders III type, IV type calcaneal fractures were retrospectively analyzed, including 16 males and 5 females, aged 22 to 55 years. After fracture reduction, a dough-like Genex bone graft was implanted into the defect region via lateral“L”shaped approach, and then the lateral wal of the bone was reset fol owed by internal fixation with the pre-curved locking plate. Fol ow-up observation was performed for fracture healing, Bolher angle and the Maryland Foot Score. RESULTS AND CONCLUSION:Total y 21 patients were fol owed up for 8-16 months. The fractures were healed without displacement, col apse and rejection. The bone graft was degraded within 6 months and completed absorbed after 1 year. According to Maryland Foot Score, the excellent rate was up to 86%, and the Bolher angle was increased from an average preoperative (5.3±3.35)° to postoperative (24.3±1.06)°. Genex artificial bone meal is a biomaterial that can be completely absorbed, has good plasticity and strong supporting force, and it is able to ful y fil bone defects, be easy to fracture reduction, induce bone formation, and promote fracture healing.