中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
39期
6271-6275
,共5页
朱洲%王生介%厉晓龙%费燕强%蒋小军
硃洲%王生介%厲曉龍%費燕彊%蔣小軍
주주%왕생개%려효룡%비연강%장소군
生物材料%骨生物材料%经皮椎体成形%骨水泥%压缩骨折%骨质疏松
生物材料%骨生物材料%經皮椎體成形%骨水泥%壓縮骨摺%骨質疏鬆
생물재료%골생물재료%경피추체성형%골수니%압축골절%골질소송
osteoporotic fractures%vertebroplasty%polymethacrylic acids
背景:经皮椎体成形治疗椎体骨折可有效缓解剧烈疼痛,具有创伤小、疗效佳及并发症少的优势,但对于骨质疏松性压缩骨折患者来说,术后存在不同程度的骨质疏松,病程较长、不易治愈,因而疼痛的缓解并不能全面评价经皮椎体成形治疗的有效性。目的:探讨经皮椎体成形治疗新鲜骨质疏松性压缩骨折的临床疗效。方法:纳入24例行经皮椎体成形治疗及同期24例进行保守治疗的新鲜骨质疏松性压缩骨折患者作为研究对象,比较两组治疗前后疼痛程度、椎体高度、后凸Cobb角度、下腰部功能活动情况、治疗后6个月的生活质量及临床并发症的发生率。结果与结论:两组患者治疗后的疼痛程度、椎体高度、后凸 Cobb 角度、下腰部功能活动情况均较治疗前明显改善(P<0.05),并且椎体成形治疗组患者的各项指标均明显优于保守治疗组(P<0.05);椎体成形治疗组治疗后6个月的生活质量也明显高于保守治疗组(P <0.05),治疗后6个月的并发症总发生率低于保守治疗组(P<0.05)。表明经皮椎体成形治疗治疗胸腰椎体新鲜骨质疏松性压缩骨折可有效缓解疼痛,改善椎体畸形,提高下腰部活动能力,提高患者生活质量。
揹景:經皮椎體成形治療椎體骨摺可有效緩解劇烈疼痛,具有創傷小、療效佳及併髮癥少的優勢,但對于骨質疏鬆性壓縮骨摺患者來說,術後存在不同程度的骨質疏鬆,病程較長、不易治愈,因而疼痛的緩解併不能全麵評價經皮椎體成形治療的有效性。目的:探討經皮椎體成形治療新鮮骨質疏鬆性壓縮骨摺的臨床療效。方法:納入24例行經皮椎體成形治療及同期24例進行保守治療的新鮮骨質疏鬆性壓縮骨摺患者作為研究對象,比較兩組治療前後疼痛程度、椎體高度、後凸Cobb角度、下腰部功能活動情況、治療後6箇月的生活質量及臨床併髮癥的髮生率。結果與結論:兩組患者治療後的疼痛程度、椎體高度、後凸 Cobb 角度、下腰部功能活動情況均較治療前明顯改善(P<0.05),併且椎體成形治療組患者的各項指標均明顯優于保守治療組(P<0.05);椎體成形治療組治療後6箇月的生活質量也明顯高于保守治療組(P <0.05),治療後6箇月的併髮癥總髮生率低于保守治療組(P<0.05)。錶明經皮椎體成形治療治療胸腰椎體新鮮骨質疏鬆性壓縮骨摺可有效緩解疼痛,改善椎體畸形,提高下腰部活動能力,提高患者生活質量。
배경:경피추체성형치료추체골절가유효완해극렬동통,구유창상소、료효가급병발증소적우세,단대우골질소송성압축골절환자래설,술후존재불동정도적골질소송,병정교장、불역치유,인이동통적완해병불능전면평개경피추체성형치료적유효성。목적:탐토경피추체성형치료신선골질소송성압축골절적림상료효。방법:납입24례행경피추체성형치료급동기24례진행보수치료적신선골질소송성압축골절환자작위연구대상,비교량조치료전후동통정도、추체고도、후철Cobb각도、하요부공능활동정황、치료후6개월적생활질량급림상병발증적발생솔。결과여결론:량조환자치료후적동통정도、추체고도、후철 Cobb 각도、하요부공능활동정황균교치료전명현개선(P<0.05),병차추체성형치료조환자적각항지표균명현우우보수치료조(P<0.05);추체성형치료조치료후6개월적생활질량야명현고우보수치료조(P <0.05),치료후6개월적병발증총발생솔저우보수치료조(P<0.05)。표명경피추체성형치료치료흉요추체신선골질소송성압축골절가유효완해동통,개선추체기형,제고하요부활동능력,제고환자생활질량。
BACKGROUND:Percutaneous vertebroplasty for vertebral fractures can effectively relieve acute pain and has the advantages of smal trauma, good curative effect and less complications, but for patients with osteoporotic compression fractures, there were varying degrees of osteoporosis after surgery, which have a longer course of disease and cannot be easy to cure. So the effectiveness of percutaneous vertebroplasty cannot be ful y evaluated based on the pain relief. OBJECTIVE:To study the curative effect of percutaneous vertebroplasty for patients with fresh osteoporotic thoracolumbar vertebral compression fractures. METHODS:We selected 24 patients undergoing percutaneous vertebroplasty and 24 patients receiving conservative treatment at the same time who had fresh osteoporotic compression fractures as research objects;and compared pain degree, vertebral body height and the kyphosis Cobb angle, function activity of the lower lumbar before and after treatment, the quality of life and clinical incidence of complications within 6 months after treatment in the two groups. RESULTS AND CONCLUSION:The degree of pain, the vertebral body height, kyphosis Cobb angle, function activity of the lower lumbar were al improved in the two groups after treatment (P<0.05), and these indexes in the percutaneous vertebroplasty group were better than those in the conservative treatment group (P<0.05). The quality of life and incidence of complications within 6 months after treatment were improved better in the percutaneous vertebroplasty group than the conservative treatment group (both P<0.05). These results suggest that the percutaneous vertebroplasty for fresh osteoporotic thoracolumbar vertebral compression fractures can effectively reduce the pain of patients, improve vertebral deformity and activities of the lower lumbar, and has obvious role in promoting the postoperative quality of life of patients.