CAJ | 학술논문

为寻找抑郁症患者早期诊断指标,采集了5例未经抗抑郁药物干预的抑郁症患者和6例正常被试者静息状态下的脑电数据,采用样本熵算法,研究抑郁症患者脑电时间序列复杂度。结果表明,2组数据睁眼状态都比闭眼状态的样本熵数值大,说明睁眼状态的时间序列复杂度要高于闭眼状态。抑郁组的睁眼状态和闭眼状态样本熵数值分别比正常组大,说明抑郁组睁眼和闭眼状态时间序列复杂度比正常组高。研究表明,样本熵的处理方法能有效区分抑郁症患者和正常对照组,样本熵可作为判别抑郁症的生物学指标,为抑郁症的早期诊断提供一种辅助方法。
위심조억욱증환자조기진단지표,채집료5례미경항억욱약물간예적억욱증환자화6례정상피시자정식상태하적뇌전수거,채용양본적산법,연구억욱증환자뇌전시간서렬복잡도。결과표명,2조수거정안상태도비폐안상태적양본적수치대,설명정안상태적시간서렬복잡도요고우폐안상태。억욱조적정안상태화폐안상태양본적수치분별비정상조대,설명억욱조정안화폐안상태시간서렬복잡도비정상조고。연구표명,양본적적처리방법능유효구분억욱증환자화정상대조조,양본적가작위판별억욱증적생물학지표,위억욱증적조기진단제공일충보조방법。
In order to find indicators for early diagnosis of depression patients,the resting EEG data is collected from 5 de-pression patients and 6 normal subj ects.Using sample entropy,time series complexity is studied on patients with depres-sion.The results shows that the sample entropy of eyes opening is higher than eyes closed in two groups.It indicates that the time series of eye opening has a higher degree of complexity than eyes closed.The depression group has a higher sample entropy than the normal group in two stages,the time series complexity of the depression group is higher than the normal group.The sample entropy can effectively distinguish depression patients with normal people.So it can be used for aiding early diagnosis of depression.