CAJ | 학술논문

免疫共沉淀技术是研究蛋白质-蛋白质之间相互作用的重要方法之一，可以确定在生理状态下细胞内相互作用的蛋白质。在蛋白复合物的研究中，不仅可以用于验证其存在，还可以发现新的蛋白复合物。近来，中医药科研工作者应用此技术来揭示中医药的作用机制，取得了一些成绩。就近几年免疫共沉淀技术的应用研究做文献综述。
면역공침정기술시연구단백질-단백질지간상호작용적중요방법지일，가이학정재생리상태하세포내상호작용적단백질。재단백복합물적연구중，불부가이용우험증기존재，환가이발현신적단백복합물。근래，중의약과연공작자응용차기술래게시중의약적작용궤제，취득료일사성적。취근궤년면역공침정기술적응용연구주문헌종술。
Co-immunoprecipitation technique is an important method to study interaction between protein-protein, which can be used to determine the interacting proteins in the intracellular physiological states. In the study of protein-protein complexes, it not only can be used to verify its existence, also can be used to find the new complex. Recently, researchers of traditional Chinese medicine (TCM) have utilized this technology to reveal the mechanism of TCM and made some achievements. This study reviewed applications of co-immunoprecipitation technique in recent years.