CAJ | 학술논문

本文以PLLA和PVA为成膜聚合物， DMSO为溶剂，通过静电纺丝方法制备了直径为600±76nm的表面光滑、均一的PLLA/PVA复合纳米纤维膜。通过扫描电镜、接触角测定仪、孔隙率测定和吸水实验，分别观察和测定纤维膜的形貌、接触角、孔隙率和吸水率。实验结果表明：加入10 wt％的PVA，纤维的形貌并没有发生改变，而纤维的直径略有增加；纤维膜的接触角由95±5闭减小为58±3闭；孔隙率由85％减小为82％。但纤维膜的吸水率从14％明显的增加到72％。因此，加入的PVA可以明显改善纤维膜的亲水性。 PL-LA/PVA复合纳米纤维膜有望作为组织工程支架材料使用。
본문이PLLA화PVA위성막취합물， DMSO위용제，통과정전방사방법제비료직경위600±76nm적표면광활、균일적PLLA/PVA복합납미섬유막。통과소묘전경、접촉각측정의、공극솔측정화흡수실험，분별관찰화측정섬유막적형모、접촉각、공극솔화흡수솔。실험결과표명：가입10 wt％적PVA，섬유적형모병몰유발생개변，이섬유적직경략유증가；섬유막적접촉각유95±5폐감소위58±3폐；공극솔유85％감소위82％。단섬유막적흡수솔종14％명현적증가도72％。인차，가입적PVA가이명현개선섬유막적친수성。 PL-LA/PVA복합납미섬유막유망작위조직공정지가재료사용。
Uniform PLLA/PVA composite nanofibers membrane with diameter of 600 ±76 nm was fabricated through electrospinning using PLLA and PVA as polymer and DMSO as solvent .The morphology , contact angle , porosity and water absorption of nanofibers membrane were characterized by SEM , contact angle meter , water absorption measure-ment respectively .The results showed that compared with PLLA nanofibers membrane , the morphology of PLLA/PVA com-posite nanofibers membrane was not changed , while the diameter was slightly increased .The contact angle and porosity of PLLA/PVA composite nanofibers membrane were decreased from 95 ±5o to 58 ±3o and 85%to 82%, respectively.How-ever, the water absorption of membrane was obviously increased from 14%to 72%, which indicates that the hydrophilcity of membrane was improved by incorporation of PVA .Due to the porous structure , this special PLLA/PVA composite nano-fibers membrane would be in favor of cell adhesion and growth , so they could be expected to be a very promising tissue en-gineering scaffold .