CAJ | 학술논문

目的：观察参麦注射液对血液透析气阴两虚型患者血管内皮功能的影响。方法：选择透析中心维持性血液透析患者60例，分为治疗组和对照组，治疗组在常规血透用药的基础上给予参麦注射液，对照组仅给予常规血透用药，治疗6个月，观察治疗前后两组患者的中医证候积分、血红蛋白、血白蛋白以及血ET-1水平的变化。结果：①治疗后，参麦组中医证候实证积分降低（ p＜0.05），其总体有效率高于对照组；②治疗后，参麦组的ET-1水平较治疗前明显降低（ P＜0.05）。结论：参麦注射液可以减轻透析患者的血管内皮细胞损伤。
목적：관찰삼맥주사액대혈액투석기음량허형환자혈관내피공능적영향。방법：선택투석중심유지성혈액투석환자60례，분위치료조화대조조，치료조재상규혈투용약적기출상급여삼맥주사액，대조조부급여상규혈투용약，치료6개월，관찰치료전후량조환자적중의증후적분、혈홍단백、혈백단백이급혈ET-1수평적변화。결과：①치료후，삼맥조중의증후실증적분강저（ p＜0.05），기총체유효솔고우대조조；②치료후，삼맥조적ET-1수평교치료전명현강저（ P＜0.05）。결론：삼맥주사액가이감경투석환자적혈관내피세포손상。
Objective:To investigate the effect of Shenmai injection on endothelial cell function in MHD pa -tients with deficiency of qi and yin syndrome.Methods:60 cases of hemodialysis patients were randomly allocated into two groups:the Shenmai group and the control group ,with 30 cases in each group.TCM syndrome scores and hemoglobin,albumin and ET -1 were determined in all patients before and after treatment.Results:After 6months’treatment,the TCM syndrome scores and ET -1 level in Shenmai group were much lower than those be-fore treatment ( P<0.05 ).Conclusion:Shenmai injection could effectively reduce the injury of vascular endo-thelial cell.