CAJ | 학술논문

多种肝脏疾病和肝外疾病可致肝脏铁过载，引起和促使肝纤维化、肝硬化。临床已有的肝脏铁含量测定方法（肝穿刺活检、实验室检查、超导量子干涉仪、MRI和CT）分别存在不同程度的局限性。其中，CT作为肝脏疾病诊断常用的检查方法，近年来在肝脏铁含量测定方面取得了长足的进步，包括单能CT 值估算法、双能CT差值法（ΔH法）和双能CT三物质分离算法（overlay法）。对CT测定肝脏铁含量的技术进展和临床应用进行综述。
다충간장질병화간외질병가치간장철과재，인기화촉사간섬유화、간경화。림상이유적간장철함량측정방법（간천자활검、실험실검사、초도양자간섭의、MRI화CT）분별존재불동정도적국한성。기중，CT작위간장질병진단상용적검사방법，근년래재간장철함량측정방면취득료장족적진보，포괄단능CT 치고산법、쌍능CT차치법（ΔH법）화쌍능CT삼물질분리산법（overlay법）。대CT측정간장철함량적기술진전화림상응용진행종술。
A variety of intra- or extra- hepatic diseases could cause iron deposition in liver which might lead to fibrosis and cirrhosis. The existing clinical methods (liver biopsy, laboratory examination, superconducting quantum interference device, MRI and CT) to quantify iron content in liver have their own disadvantages respectively. Meanwhile, CT has been a popular diagnostic method for liver disease, and made considerable development in quantifying liver iron content, including single-energy CT value estimate method, dual-energy CT differential method (ΔH method) and dual-energy CT three-material decomposition algorithm (overlay method). In this paper, we reviewed the current status of technical developments and clinical applications of CT in the quantification measurement of liver iron content.