国际老年医学杂志
國際老年醫學雜誌
국제노년의학잡지
INTERNATIONAL JOURNAL OF GERIATRICS
2014年
5期
193-196,209
,共5页
维吾尔族%单纯收缩期高血压%超敏C反应蛋白%颈动脉内膜-中层厚度%脉搏波传导速度
維吾爾族%單純收縮期高血壓%超敏C反應蛋白%頸動脈內膜-中層厚度%脈搏波傳導速度
유오이족%단순수축기고혈압%초민C반응단백%경동맥내막-중층후도%맥박파전도속도
Uygur%Isolated systolic hypertension%High-sensitivity C-reactive protein%Carotid intima-media thickness%Pulse wave velocity
目的：探讨维吾尔族老年收缩期高血压( ISH)患者超敏C反应蛋白( hs-CRP)与颈-股动脉的脉搏波传导速度( cfPWV)及颈动脉内膜-中层厚度( IMT)的相关性。方法：选取维吾尔族老年ISH患者118例作为ISH组,维吾尔族老年原发性高血压( EH)患者115例作为EH组,并选择年龄与之相匹配的维吾尔族血压正常人群( NT)100例作为NT组。采用免疫透射比浊法测定血清hs-CRP水平；超声技术测定IMT,动脉硬化检测仪测定cfPWV。采用直线相关分析法分析hs-CRP与cfPWV及IMT的相关性。结果： ISH组、 EH组hs-CRP、 cfPWV及IMT均高于NT组( P<0．05)；ISH组hs-CRP、 cfPWV及 IMT 均高于 NT 组( P <0．05)。相关性分析表明, hs -CRP 与 cfPWV、 IMT 呈正相关( P <0．001)。结论：维吾尔族老ISH患者血清hs-CRP水平明显升高,且与cfPWV及IMT呈正相关。
目的：探討維吾爾族老年收縮期高血壓( ISH)患者超敏C反應蛋白( hs-CRP)與頸-股動脈的脈搏波傳導速度( cfPWV)及頸動脈內膜-中層厚度( IMT)的相關性。方法：選取維吾爾族老年ISH患者118例作為ISH組,維吾爾族老年原髮性高血壓( EH)患者115例作為EH組,併選擇年齡與之相匹配的維吾爾族血壓正常人群( NT)100例作為NT組。採用免疫透射比濁法測定血清hs-CRP水平；超聲技術測定IMT,動脈硬化檢測儀測定cfPWV。採用直線相關分析法分析hs-CRP與cfPWV及IMT的相關性。結果： ISH組、 EH組hs-CRP、 cfPWV及IMT均高于NT組( P<0．05)；ISH組hs-CRP、 cfPWV及 IMT 均高于 NT 組( P <0．05)。相關性分析錶明, hs -CRP 與 cfPWV、 IMT 呈正相關( P <0．001)。結論：維吾爾族老ISH患者血清hs-CRP水平明顯升高,且與cfPWV及IMT呈正相關。
목적：탐토유오이족노년수축기고혈압( ISH)환자초민C반응단백( hs-CRP)여경-고동맥적맥박파전도속도( cfPWV)급경동맥내막-중층후도( IMT)적상관성。방법：선취유오이족노년ISH환자118례작위ISH조,유오이족노년원발성고혈압( EH)환자115례작위EH조,병선택년령여지상필배적유오이족혈압정상인군( NT)100례작위NT조。채용면역투사비탁법측정혈청hs-CRP수평；초성기술측정IMT,동맥경화검측의측정cfPWV。채용직선상관분석법분석hs-CRP여cfPWV급IMT적상관성。결과： ISH조、 EH조hs-CRP、 cfPWV급IMT균고우NT조( P<0．05)；ISH조hs-CRP、 cfPWV급 IMT 균고우 NT 조( P <0．05)。상관성분석표명, hs -CRP 여 cfPWV、 IMT 정정상관( P <0．001)。결론：유오이족로ISH환자혈청hs-CRP수평명현승고,차여cfPWV급IMT정정상관。
OBJECTIVE: To investigate the association among high-sensitivity C-reactive protein ( hs-CRP) , carotid-fem-oral pulse wave conduction velocity ( cfPWV) and carotid intima-media thickness ( IMT) of Uygur elderly patients with isolated sys-tolic hypertension ( ISH) . METHODS: 118 Uygur old patients with isolated systolic hypertension ( ISH) were enrolled as ISH group. 115 patients with essential hypertension ( EH) were the EH group. Another 100 age-matched normotension ( NT) people were cho-sen as NT group. Serum hs-CRP was measured by turbidimetric immunoassay method. IMT was detected through ultrasound technol-ogy and cfPWV was measured by automatic arteriosclerosis detector. The association among hs-CRP, cf-PWV and IMT was de-scribed by linear correlation analysis. RESULTS: hs-CRP, cfPWV and IMT in ISH and EH groups were higher than those in NT group (P<0. 05), while the hs-CRP, cfPWV and IMT in ISH group were all higher than those in EH group (P<0. 05). The studies showed that hs-CRP was positively correlated with cfPWV and IMT (P<0. 001). CONCLUSION: hs-CRP level is signifi-cantly elevated in Uygur elderly patients with ISH and positively correlated with cfPWV and IMT.
