胃肠病学
胃腸病學
위장병학
CHINESE JOURNAL OF GASTROENTEROLOGY
2014年
7期
439-441
,共3页
降钙素原%胰腺炎%疾病严重程度%C反应蛋白质%诊断
降鈣素原%胰腺炎%疾病嚴重程度%C反應蛋白質%診斷
강개소원%이선염%질병엄중정도%C반응단백질%진단
Procalcitonin%Pancreatitis%SeverityofDisease%C-ReactiveProtein%Diagnosis
急性胰腺炎( AP)是一种常见急腹症,可分为轻度AP( MAP)、中度AP( MSAP)和重度AP( SAP)。MAP、MSAP多具有自限性,预后良好,而SAP常伴有诸多局部和(或)系统性并发症,死亡率高。因此,及早判断AP严重程度对临床诊治具有重要意义。降钙素原( PCT)是降钙素的前肽物质,作为一种炎症介质可用于鉴别细菌性与非细菌性感染。近年来,PCT在AP中的作用越来越受到医学界的关注,本文就PCT与AP的研究进展作一综述。
急性胰腺炎( AP)是一種常見急腹癥,可分為輕度AP( MAP)、中度AP( MSAP)和重度AP( SAP)。MAP、MSAP多具有自限性,預後良好,而SAP常伴有諸多跼部和(或)繫統性併髮癥,死亡率高。因此,及早判斷AP嚴重程度對臨床診治具有重要意義。降鈣素原( PCT)是降鈣素的前肽物質,作為一種炎癥介質可用于鑒彆細菌性與非細菌性感染。近年來,PCT在AP中的作用越來越受到醫學界的關註,本文就PCT與AP的研究進展作一綜述。
급성이선염( AP)시일충상견급복증,가분위경도AP( MAP)、중도AP( MSAP)화중도AP( SAP)。MAP、MSAP다구유자한성,예후량호,이SAP상반유제다국부화(혹)계통성병발증,사망솔고。인차,급조판단AP엄중정도대림상진치구유중요의의。강개소원( PCT)시강개소적전태물질,작위일충염증개질가용우감별세균성여비세균성감염。근년래,PCT재AP중적작용월래월수도의학계적관주,본문취PCT여AP적연구진전작일종술。
Acute pancreatitis( AP)is a common gastrointestinal emergency,which comprises mild acute pancreatitis ( MAP),moderately severe acute pancreatitis( MSAP)and severe acute pancreatitis( SAP). Most patients with MAP and MSAP present as a mild,self-limiting disease with low morbidity and mortality,however,patients who suffer from SAP will experience serious local and/or systemic complications associated with high mortality. Therefore,early assessment of disease severity is important for clinical management. Procalcitonin( PCT),a pro-peptide of calcitonin,is an inflammatory mediator that can be used to differentiate bacterial and non-bacterial infection. Recently,the effect of PCT on AP has attracted more and more attentions. This article reviewed the advances in studies on PCT and AP.