CAJ | 학술논문

目的：探讨血糖控制良好的糖尿病是否仍然是老年男性下尿路症状（LUTS）的危险因素之一。方法收集172例年龄≥60岁参与我院体检的老年男性的国际前列腺症状（IPSS）评分，潴尿期（storage）评分，排尿期（voiding）评分，急迫性尿失禁病史，经直肠前列腺超声（TRUS）以及前列腺特异性抗原（PSA）的资料，将患者分为两组，糖尿病控制稳定组52例，糖化血红蛋白（HbAlc）均＜7%，非糖尿病组120例。比较两组患者各指标是否有差异，并计算糖尿病与LUTS的相关性，并做回归分析。结果糖尿病控制稳定组患者的IPSS评分，storage评分，voiding评分及急迫性尿失禁发生率均显著高于非糖尿病组患者（P均＜0.05）。糖尿病患者患病病程与IPSS评分，storage评分及voiding评分均呈显著相关性（P均＜0.05）。糖尿病本身及糖尿病患病病程均为LUTS的危险因素（OR值分别为1.772及1.098，P均＜0.05）。结论糖尿病即使血糖控制良好，仍是老年男性LUTS的危险因素，并随着患病病程的增加，症状的严重程度逐渐升高。
목적：탐토혈당공제량호적당뇨병시부잉연시노년남성하뇨로증상（LUTS）적위험인소지일。방법수집172례년령≥60세삼여아원체검적노년남성적국제전렬선증상（IPSS）평분，저뇨기（storage）평분，배뇨기（voiding）평분，급박성뇨실금병사，경직장전렬선초성（TRUS）이급전렬선특이성항원（PSA）적자료，장환자분위량조，당뇨병공제은정조52례，당화혈홍단백（HbAlc）균＜7%，비당뇨병조120례。비교량조환자각지표시부유차이，병계산당뇨병여LUTS적상관성，병주회귀분석。결과당뇨병공제은정조환자적IPSS평분，storage평분，voiding평분급급박성뇨실금발생솔균현저고우비당뇨병조환자（P균＜0.05）。당뇨병환자환병병정여IPSS평분，storage평분급voiding평분균정현저상관성（P균＜0.05）。당뇨병본신급당뇨병환병병정균위LUTS적위험인소（OR치분별위1.772급1.098，P균＜0.05）。결론당뇨병즉사혈당공제량호，잉시노년남성LUTS적위험인소，병수착환병병정적증가，증상적엄중정도축점승고。
Objective To investigate whether diabetes with good glucose control is the risk factor for lower urinary tract symptoms in elderly males or not. Methods 172 patients with age≥60 were enrolled in our study, including 52 patients with diabetes and HbA1C<7%, and 120 patients without diabetes. All the patients were required for IPSS, storage and voiding score, history of incontinence, examination of prostate ultrasound and serum PSA level.statistical analysis, including t test, spearman analysis and regression analysis, was used for comparison between two groups and the correlation between diabetes and lower urinary tract symptoms. Results IPSS, storage and voiding score, history of incontinence in the group with diabetes were significantly higher than the group without diabetes (P<0.05). Years with diabetes were significantly correlated with IPSS, storage and voiding score (P<0.05). The risk factor for lower urinary tract symptoms were both diabetes with good glucose control (OR 1.77) and years of diabetes (OR 1.098). Conclusion No matter whether diabetes patients have good or bad glucose control, diabetes is still the risk factor for lower urinary tract symptoms. Lower urinary tract symptoms will be more severe with progression of diabetes.