CAJ | 학술논문

内脏高敏感是功能性胃肠病（ FGIDs）的核心发病机制。大量研究表明精神心理应激在内脏高敏感的发生、发展中起关键作用。大脑中枢是参与精神心理应激致内脏高敏感的关键部位，尤其是高级中枢致敏，但其具体病理生理机制尚待明确。本文就精神应激诱发内脏高敏感的中枢作用机制的研究作一综述。
내장고민감시공능성위장병（ FGIDs）적핵심발병궤제。대량연구표명정신심리응격재내장고민감적발생、발전중기관건작용。대뇌중추시삼여정신심리응격치내장고민감적관건부위，우기시고급중추치민，단기구체병리생리궤제상대명학。본문취정신응격유발내장고민감적중추작용궤제적연구작일종술。
Visceral hypersensitivity is the core pathogenesis process of functional gastrointestinal disorders( FGIDs). Numerous studies showed that psychological stress plays a key role in the development of visceral hypersensitivity. Brain center is the key part involved in psychological stress-induced visceral hypersensitivity, especially senior central sensitization. However,the specific pathophysiological mechanism remains unclear. This article reviewed studies on central role mechanism of psychological stress-induced visceral hypersensitivity.