CAJ | 학술논문

目的：探讨疟疾快速诊断试剂盒临床应用效果，为临床应用提供参考。方法快速诊断试剂盒与镜检法对103例疟疾、疑似疟疾进行检测对比分析。结果镜检疟原虫阳性23例（Pf 11例、Pv 10例、Pm和Po各1例），阳性率22.33%；快速诊断试剂盒检测疟原虫阳性22例（Pf 11例、Pv 10例、Pm 1例），阳性率21.36%，卵形疟未检出。两方法检出阳性率无统计学意义（χ2=0.33，P>0.05）。该试剂的总灵敏性95.65%，总特异性97.50%，阳性预测值91.67%，阴性预测值98.73%，漏检率4.35%，误诊率2.50%。结论疟疾快速诊断试剂盒具有良好的疟疾诊断效果和简便、快速等优点，非常适合镜检技术和条件不足的基层医疗、预防机构开展疟疾检测。
목적：탐토학질쾌속진단시제합림상응용효과，위림상응용제공삼고。방법쾌속진단시제합여경검법대103례학질、의사학질진행검측대비분석。결과경검학원충양성23례（Pf 11례、Pv 10례、Pm화Po각1례），양성솔22.33%；쾌속진단시제합검측학원충양성22례（Pf 11례、Pv 10례、Pm 1례），양성솔21.36%，란형학미검출。량방법검출양성솔무통계학의의（χ2=0.33，P>0.05）。해시제적총령민성95.65%，총특이성97.50%，양성예측치91.67%，음성예측치98.73%，루검솔4.35%，오진솔2.50%。결론학질쾌속진단시제합구유량호적학질진단효과화간편、쾌속등우점，비상괄합경검기술화조건불족적기층의료、예방궤구개전학질검측。
Objective To probe the effect of rapid diagnostic test in the diagnosis of malaria, and pro-vide reference for clinical application. Methods 103 suspicious cases of malaria were checked with rapid diag-nostic test and microscopy method. Results 23 positive cases were detected by microscopy method (Pf 11 cas-es, Pv 10 cases, Pm and Po 1 case each) with positive rate of 22.33%, and 22 positive cases were detected by rapid diagnostic test (Pf 11 cases, Pv 10 cases, Pm 1 case) with positive rate of 21.36%. One Po case was not detected by rapid diagnostic test. There was no significant difference between the two methods (χ2=0.33, P>0.05). The sensitivity of the rapid diagnostic test was 95.65%, with the specificity of 97.5%, the positive predic-tive value of 91.67%, the negative predictive value of 98.73%, the missing rate of 4.35%, and the misdiagnosis rate of 2.50%. Conclusion The rapid diagnostic test had good effect on the diagnosis of malaria with advan-tage of simple and fast, and very suitable for grass-roots level medical treatment and disease prevention units which have insufficient microscopy equipment and techniques to carry out the diagnosis of malaria.