CAJ | 학술논문

目的：探讨全胸腔镜下食管癌根治术手术效果，及其对炎症因子、患者生存质量的影响。方法将2009年2月至2012年2月于本院治疗的68例食管癌患者随机分为对照组（32例）和观察组（36例），对照组给予传统食管癌根治术治疗，观察组给予全胸腔镜下食管癌根治术治疗。比较两组手术效果、术后炎症因子水平及患者生存质量。结果观察组手术时间、出血量、胸引流管保留时间均少于对照组（ P＜0．05）。术后24 h观察组超敏C反应蛋白、肿瘤坏死因子-α及白细胞介素-6水平均低于对照组（P＜0．05）。术后3个月时，观察组患者生存质量量表（S F-36量表）各项目评分及总体评分均优于对照组（ P＜0．05）。结论与传统食管癌根治术相比，全胸腔镜下食管癌根治术创伤小，术后炎性反应程度轻，可有效提高患者生存质量。
목적：탐토전흉강경하식관암근치술수술효과，급기대염증인자、환자생존질량적영향。방법장2009년2월지2012년2월우본원치료적68례식관암환자수궤분위대조조（32례）화관찰조（36례），대조조급여전통식관암근치술치료，관찰조급여전흉강경하식관암근치술치료。비교량조수술효과、술후염증인자수평급환자생존질량。결과관찰조수술시간、출혈량、흉인류관보류시간균소우대조조（ P＜0．05）。술후24 h관찰조초민C반응단백、종류배사인자-α급백세포개소-6수평균저우대조조（P＜0．05）。술후3개월시，관찰조환자생존질량량표（S F-36량표）각항목평분급총체평분균우우대조조（ P＜0．05）。결론여전통식관암근치술상비，전흉강경하식관암근치술창상소，술후염성반응정도경，가유효제고환자생존질량。
Objective To explore the operation effect and influence of total thoracoscopy resection of esopha-geal cancer on inflammatory factors and quality of life .Methods From Feb .2009 to Feb .2012 ,a total of 68 patients with esophageal cancer were randomly divided into control group (32 cases) ,receiving conventional radical operation , and observation group (36 cases) ,receiving total thoracoscopy resection .Operation effect ,serum levels of inflamma-tory factors ,and life quality were compared between the two groups .Results Operation time ,volume of blood loss , time of postoperative keeping of chest tube in observation group were shorter than control group (P<0 .05) .Serum levels of high sensitivity-C reaction protein ,tumor necrosis factor-αand interleukin-6 detected at 24 h after operation in observation group were lower than control group(P<0 .05) .Scores of life quality scale (SF-36 scale) in observa-tion group were superior to control group (P<0 .05) .Conclusion Compared with conventional radical operation ,to-tal thoracoscopy resection of esophageal carcinoma might be with less injure ,which could decrease postoperative in-flammatory response and improve life quality of patients .