CAJ | 학술논문

心肌收缩功能是维持血流动力学、保证组织灌流的中心环节。心肌收缩功能障碍是失血性休克后微循环障碍、器官低灌注、组织细胞损伤的关键因素，钙在心肌电活动中的兴奋-收缩耦联过程中发挥重要作用。本文重点从钙依赖途径与钙敏感途径两方面综述失血性休克后心肌收缩功能障碍的钙调节机制，为防治失血性休克后心肌收缩功能障碍提供依据。
심기수축공능시유지혈류동역학、보증조직관류적중심배절。심기수축공능장애시실혈성휴극후미순배장애、기관저관주、조직세포손상적관건인소，개재심기전활동중적흥강-수축우련과정중발휘중요작용。본문중점종개의뢰도경여개민감도경량방면종술실혈성휴극후심기수축공능장애적개조절궤제，위방치실혈성휴극후심기수축공능장애제공의거。
Myocardialcontractilefunctionisakeylinkformaintaininghemodynamicsandorganizationoerfusion.My-ocardial contractile dysfunction is a vital factor in microcirculation dysfunction,organ hyoooerfusion,and tissue or cell injuries following hemorrhagic shock. The calcium olay an imoortant oart in excitation-contraction couoling in cardiac electrical activi-ties. This article reviews the regulating mechanisms of calcium in the myocardial contractile dysfunction from the asoects of calci-um deoendent and sensitivity,to orovide a novel aooroach for treatment of myocardial contractile dysfunction following hemorrhag-ic shock.