CAJ | 학술논문

目的：探讨并研究血清降钙素原(PCT)在儿童下呼吸道感染的临床意义。方法160例下呼吸道感染的患儿作为临床研究对象，随机分为两组进行治疗。对照组(80例)采用常规的方式进行治疗，实验组(80例)采用在血清降钙素原(PCT)指导下进行抗生素治疗。结果实验组进行抗生素治疗时间较短，且实验组肺炎患儿在抗生素使用中明显比对照组少30%，差异具有统计学意义(P<0.05)。结论实验组在血清降钙素原指导下针对儿童下呼吸道感染的患儿使用抗生素治疗效果较好，能够使患儿减少使用不必要的抗生素，对于临床治疗有较为重要的意义。
목적：탐토병연구혈청강개소원(PCT)재인동하호흡도감염적림상의의。방법160례하호흡도감염적환인작위림상연구대상，수궤분위량조진행치료。대조조(80례)채용상규적방식진행치료，실험조(80례)채용재혈청강개소원(PCT)지도하진행항생소치료。결과실험조진행항생소치료시간교단，차실험조폐염환인재항생소사용중명현비대조조소30%，차이구유통계학의의(P<0.05)。결론실험조재혈청강개소원지도하침대인동하호흡도감염적환인사용항생소치료효과교호，능구사환인감소사용불필요적항생소，대우림상치료유교위중요적의의。
Objective To explore and study the clinical significance of applying serum procalcitionin (PCT) in the treatment of children with lower respiratory tract infection (LRTI). Methods A total of 160 children of LRTI were selected as the study objects and randomly divided into 2 groups. The control group (n=80) was treated by convnetional method, and the experimental group (n=80) was treated by antibiotic under the guidance of PCT. Results The time of antibiotic therapy and the amount of antibiotic used in the experimental group for children with pneumonia were all less than the control group, and the differences had statistical significance (P<0.05). Conclusion The efficacy of antibiotics under PCT guidance in the treatment of children LPTI is good. The therapy can help to reduce unnecessary antibiotics for children patients, and it has important significances for clinical treatment.