CAJ | 학술논문

目的：探讨终末期肾病维持性血液透析(maintenance hemodialysis, MHD)患者不同液体超负荷水平与心率变异性(heart rate variability, HRV)的关系。方法终末期肾病MHD患者60例,根据透析期间患者体重增长情况，将入选患者透析期间体重增长不超过5%的归入对照组,共47例；因患者自身原因(透析不充分、饮水过多及气候变化等)透析期间体重增长超过5%的归入实验组,共13例,分析同一MHD患者透析后不同液体超负荷水平与HRV的关系。结果两组比较,高频功率(high frequency, HF)差异无统计学意义(P>0.05),低频功率(low frequency, LF)及R-R间期功率变异比值(LF/HF)差异有统计学意义(P<0.05)。近似熵(ApEn)在透析前差异无统计学意义(P>0.05),透析后差异有统计学意义(P<0.05)。结论透析期间控制液体负荷水平可能有助于心脏自主神经功能的改善。
목적：탐토종말기신병유지성혈액투석(maintenance hemodialysis, MHD)환자불동액체초부하수평여심솔변이성(heart rate variability, HRV)적관계。방법종말기신병MHD환자60례,근거투석기간환자체중증장정황，장입선환자투석기간체중증장불초과5%적귀입대조조,공47례；인환자자신원인(투석불충분、음수과다급기후변화등)투석기간체중증장초과5%적귀입실험조,공13례,분석동일MHD환자투석후불동액체초부하수평여HRV적관계。결과량조비교,고빈공솔(high frequency, HF)차이무통계학의의(P>0.05),저빈공솔(low frequency, LF)급R-R간기공솔변이비치(LF/HF)차이유통계학의의(P<0.05)。근사적(ApEn)재투석전차이무통계학의의(P>0.05),투석후차이유통계학의의(P<0.05)。결론투석기간공제액체부하수평가능유조우심장자주신경공능적개선。
Objective To investigate the relationship between liquid overload level and heart rate variability (HRV) in end-stage renal disease patients undergone maintenance hemodialysis (MHD). Methods There were 60 cases of end-stage renal disease with MHD. According to ponderal growth of patients during hemodialysis, 47 cases with ponderal growth less than 5%were divided into the control group, and 13 cases with ponderal growth more than 5%due to personal reasons (inadequate hemodialysis, too much drinking and climate change) were divided into experimental group. The relationship between different liquid overload level and HRV was analyzed in the same MHD patients. Results The comparison showed that the difference of high frequency (HF) had no statistical significance (P>0.05), while the differences of low frequency (LF) and the R-R interphase variation ratio (LF/HF) between the experimental group and the control group were statistically significant (P<0.05). The difference of approximate entropy (ApEn) before hemodialysis had no statistical significance (P>0.05), the difference after hemodialysis was statistically significant (P<0.05). Conclusion Control of liquid overload level during hemodialysis may promote the improvement of cardiac autonomic nervous system.