CAJ | 학술논문

目的：制订羚羊清肺颗粒中冰片的含量测定方法。方法采用《中国药典》2010年版一部附录ⅥE规定的气相色谱测定方法：色谱柱：HP20M(30 m×0.32 mm×1.0μm)(PEG20M)；柱温：140℃；气化温度：280℃；检测器温度：300℃；载气：氮气(色谱纯)；流速：35.5 mL/min；分流比：40：1；进样量：1μL。结果羚羊清肺颗粒中冰片称样量在1.85~11.13 mg范围内呈良好的线性关系，平均回收率在97.71%~101.24%之间，RSD为1.35%(n越6)，符合《中国药典》2010年版一部规定，其他方法学考查均符合《中国药典》2010年版一部规定。结论本研究所采用的气相色谱法操作快速、简便、易行，精密度、重复性、稳定性好，可用于羚羊清肺颗粒中冰片的含量测定。
목적：제정령양청폐과립중빙편적함량측정방법。방법채용《중국약전》2010년판일부부록ⅥE규정적기상색보측정방법：색보주：HP20M(30 m×0.32 mm×1.0μm)(PEG20M)；주온：140℃；기화온도：280℃；검측기온도：300℃；재기：담기(색보순)；류속：35.5 mL/min；분류비：40：1；진양량：1μL。결과령양청폐과립중빙편칭양량재1.85~11.13 mg범위내정량호적선성관계，평균회수솔재97.71%~101.24%지간，RSD위1.35%(n월6)，부합《중국약전》2010년판일부규정，기타방법학고사균부합《중국약전》2010년판일부규정。결론본연구소채용적기상색보법조작쾌속、간편、역행，정밀도、중복성、은정성호，가용우령양청폐과립중빙편적함량측정。
Objective To establish a method for determination of the borneol content of Lingyang Qingfei Granules. Methods Gas chromatography in Appendix ⅥE of Chinese Pharmacopeia (2010 edition, 1 volume) determination was used as follow: chromatographic column: HP20M (30 mí0.32 mmí1.0 μm) (PEG20M); column temperature: 140℃;gasification temperature: 280℃; detector temperature: 300℃; carrier gas: Nitrogen (chromatographic purity); flow rate:35.5 mL/min, the split ratio: 40:1; sample size: 1 μL. Results Borneol of Lingyang Qingfei Granules in the sample weight in the range of 1.85-11.13 mg showed a good linear relationship, the average rate of recovery was 97.71%-101.24%, RSD was 1.35% (n=6), in accordance with the relevant provisions, other methods of study were in confor-mity with the relevant provisions. Conclusion This method of GC is rapid, simple, and convenient to operate, its preci-sion, repeatability and stability are all good, it can be used for the content determination of borneol of Lingyang Qingfei Granules.