CAJ | 학술논문

目的：观察局部冷冻或外用药物联合光动力治疗肛管内尖锐湿疣(CA)的疗效。方法采用局部冷冻或外用药物联合光动力治疗51例肛管内CA患者，光动力疗法7～10 d 治疗1次，共2～5次。于治疗结束后2、4、8、12周对疣体完全清除者进行随访，观察治疗情况。结果51例患者中47例疣体完全清除，疣体清除率为92.16%（47/51），其中41例痊愈，治愈率为87.23%（41/47）。随访疣体完全清除者中4例在治疗后8周复发，2例在12周内复发，复发率为12.77%（6/47）。结论局部冷冻或外用药物联合光动力治疗肛管内CA安全、有效。
목적：관찰국부냉동혹외용약물연합광동력치료항관내첨예습우(CA)적료효。방법채용국부냉동혹외용약물연합광동력치료51례항관내CA환자，광동력요법7～10 d 치료1차，공2～5차。우치료결속후2、4、8、12주대우체완전청제자진행수방，관찰치료정황。결과51례환자중47례우체완전청제，우체청제솔위92.16%（47/51），기중41례전유，치유솔위87.23%（41/47）。수방우체완전청제자중4례재치료후8주복발，2례재12주내복발，복발솔위12.77%（6/47）。결론국부냉동혹외용약물연합광동력치료항관내CA안전、유효。
Objective To observe the curative effect of cryotherapy or externally applied agents combined with photodynamic therapy in the treatment of anal canal condyloma acuminatum. Methods Fifty one patients who had condyloma acuminatum in anal canal were treated by cryotherapy or externally applied agents combined with photodynamic therapy, and the photodynamic therapy was given every 7 to 10 days, a total of 2 to 5 times. The patients who removed the verrucous body after the treatment were followed-up at 2, 4, 8, 12 weeks. Results Among the 51 cases, 47 cases’ verrucous body were completely removed, including recovery 41 cases. Follow-up the wart body completely removed patients, 4 cases relapsed in 8 weeks after treatment, 2 cases relapsed in 12 weeks. The wart body clearance rate was 92.16%(47/51), the cure rate was 87.23%(41/47), the recurrence rate was 12.76%(6/47). Conclusion Cryotherapy or externally applied agents combined with photodynamic therapy for the treatment of condyloma in anal canal is safe and effective.