CAJ | 학술논문

目的：评价人工泪液治疗白内障术后干眼症的临床效果。方法选择2011年5月~2013年5月于本院就诊的350例白内障术后干眼症患者，随机分为试验组和对照组各175例，两组患者均采用超声乳化白内障吸除术治疗白内障，术后对照组给予常规治疗，试验组在常规治疗的基础上加用人工泪液，记录两组治疗前后的泪液分泌检查(SIT)、角膜荧光素染色检查(FL)、泪膜破裂时间检查(BUT)水平及临床疗效，观察用药期间患者的不良反应情况。结果治疗前两组患者的SIT、FL、BUT水平差异无统计学意义(P>0.05)，治疗后SIT、FL、BUT水平均显著改善，与治疗前比较，差异有统计学意义(P<0.05)，且治疗后试验组的SIT、FL、BUT改善水平均优于对照组，差异有统计学意义(P<0.05)；试验组的总有效率(93.1%)显著高于对照组(79.4%)，差异有统计学意义(χ2=13.9073，P=0.0002)；两组患者用药期间未发现明显不良反应情况。结论人工泪液治疗白内障术后干眼症，效果显著，适合临床推广应用。
목적：평개인공루액치료백내장술후간안증적림상효과。방법선택2011년5월~2013년5월우본원취진적350례백내장술후간안증환자，수궤분위시험조화대조조각175례，량조환자균채용초성유화백내장흡제술치료백내장，술후대조조급여상규치료，시험조재상규치료적기출상가용인공루액，기록량조치료전후적루액분비검사(SIT)、각막형광소염색검사(FL)、루막파렬시간검사(BUT)수평급림상료효，관찰용약기간환자적불량반응정황。결과치료전량조환자적SIT、FL、BUT수평차이무통계학의의(P>0.05)，치료후SIT、FL、BUT수평균현저개선，여치료전비교，차이유통계학의의(P<0.05)，차치료후시험조적SIT、FL、BUT개선수평균우우대조조，차이유통계학의의(P<0.05)；시험조적총유효솔(93.1%)현저고우대조조(79.4%)，차이유통계학의의(χ2=13.9073，P=0.0002)；량조환자용약기간미발현명현불량반응정황。결론인공루액치료백내장술후간안증，효과현저，괄합림상추엄응용。
Objective To evaluate the curative effect of artificial tears in the treatment of xerophthalmia after cataract surgery. Methods 350 patients with xerophthalmia after cataract surgeries who visited our hospital for treatment from May 2011 to May 2013 were selected.They were evenly divided into experimental group and control group in random. Phacoemulsification for cataract was applied in both groups.After surgery,regular treatment was provided in the control group,while artificial tears was added to the experimental group on the basis of regular treatment.The levels of schirmer test (SIT),corneal fluorescein staining (FL),break-up time (BUT) before and after treatment and the clinical effect after therapy were recorded in the two groups.The adverse reactions during medication were observed. Results Before treat-ment,the levels of SIT,FL,and BUT had no statistical differences in the two groups (P>0.05).After therapy,levels in these indexes all remarkably changed and indicated statistical differences compared with before treatment (P<0.05).The im-provement of these indexes after treatment in the experimental group were all superior to those in the control group,with statistical differences (P<0.05).After therapy,the total effective rate in the experimental group was 93.1%,much higher than 79.4%in the control group,with statistical difference (χ2=13.9073,P=0.0002).No obvious adverse reactions occurred in the two groups during medication. Conclusion Artificial tears can effectively treat patient with xerophthalmia after cataract surgery.It can obtain a remarkable clinical effect and is worthy of expansion and application in clinic.