中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2014年
28期
35-36
,共2页
阿卡波糖%二甲双胍%冠心病%2型糖尿病
阿卡波糖%二甲雙胍%冠心病%2型糖尿病
아잡파당%이갑쌍고%관심병%2형당뇨병
Acarbose%Metformin%Coronary heart disease%Type 2 diabetes mellitus
目的：探讨阿卡波糖联合二甲双胍治疗2型糖尿病伴冠心病患者的临床效果。方法：2010年2月-2012年12月收治2型糖尿病伴冠心病患者98例，随机分为对照组和观察组，各49例。对照组给予二甲双胍进行治疗，观察组给予阿卡波糖与二甲双胍联合治疗，两组患者均接受12周治疗。治疗结束后对两组患者空腹血糖、餐后2 h血糖、超敏C反应蛋白、颈动脉内膜中层厚度进行复查，比较两组的治疗效果。结果：两组患者治疗后血糖、超敏C反应蛋白(hs-crp)、颈动脉内膜中层厚度(IMT)比较差异有统计学意义(P＜0.05)，两组在治疗期间均未出现严重不良反应，两组比较差异无统计学意义(P＞0.05)。结论：阿卡波糖联合二甲双胍对于2型糖尿病伴冠心病患者的治疗效果显著，可改善冠心病的预后，且安全有效，值得在临床上广泛推广和使用。
目的：探討阿卡波糖聯閤二甲雙胍治療2型糖尿病伴冠心病患者的臨床效果。方法：2010年2月-2012年12月收治2型糖尿病伴冠心病患者98例，隨機分為對照組和觀察組，各49例。對照組給予二甲雙胍進行治療，觀察組給予阿卡波糖與二甲雙胍聯閤治療，兩組患者均接受12週治療。治療結束後對兩組患者空腹血糖、餐後2 h血糖、超敏C反應蛋白、頸動脈內膜中層厚度進行複查，比較兩組的治療效果。結果：兩組患者治療後血糖、超敏C反應蛋白(hs-crp)、頸動脈內膜中層厚度(IMT)比較差異有統計學意義(P＜0.05)，兩組在治療期間均未齣現嚴重不良反應，兩組比較差異無統計學意義(P＞0.05)。結論：阿卡波糖聯閤二甲雙胍對于2型糖尿病伴冠心病患者的治療效果顯著，可改善冠心病的預後，且安全有效，值得在臨床上廣汎推廣和使用。
목적：탐토아잡파당연합이갑쌍고치료2형당뇨병반관심병환자적림상효과。방법：2010년2월-2012년12월수치2형당뇨병반관심병환자98례，수궤분위대조조화관찰조，각49례。대조조급여이갑쌍고진행치료，관찰조급여아잡파당여이갑쌍고연합치료，량조환자균접수12주치료。치료결속후대량조환자공복혈당、찬후2 h혈당、초민C반응단백、경동맥내막중층후도진행복사，비교량조적치료효과。결과：량조환자치료후혈당、초민C반응단백(hs-crp)、경동맥내막중층후도(IMT)비교차이유통계학의의(P＜0.05)，량조재치료기간균미출현엄중불량반응，량조비교차이무통계학의의(P＞0.05)。결론：아잡파당연합이갑쌍고대우2형당뇨병반관심병환자적치료효과현저，가개선관심병적예후，차안전유효，치득재림상상엄범추엄화사용。
Objective:To investigate the clinical efficacy of acarbose and metformin in the treatment of type 2 diabetes mellitus patients with coronary heart disease.Methods:98 cases of type 2 diabetes mellitus complicated with coronary heart disease were selected from February 2010 to December 2012.They were randomly divided into the control group and the observation group with 49 cases in each.Patients in the control group were given metformin treatment.Patients in the observation group were received acarbose and metformin treatment.Both of the groups were treated for 12 weeks.After the treatment, the fasting blood glucose,2 hours postprandial blood glucose,high sensitive C reactive protein and carotid artery intima-media thickness of patients in 2 groups were reviewed,then we compared the treatment effect of 2 groups.Results:After the treatment,the difference in blood sugar, high sensitive C reactive protein(hs-CRP) and carotid artery intima-media thickness(IMT) were statistically significant between the two groups(P<0.05);there were no serious adverse reactions during the treatment,and the differences was no significant between the two groups(P>0.05).Conclusion:Acarbose and metformin treated on patients with type 2 diabetes mellitus complicated with coronary heart disease can achieved remarkable curative effect,and can improve the prognosis of coronary heart disease.It is safe and effective.So it is worthy of extensive promotion and clinical use.
