国际移植与血液净化杂志
國際移植與血液淨化雜誌
국제이식여혈액정화잡지
INTERNATIONAL JOURNAL OF TRANSPLANTATION AND HEMOPURIFICATION
2013年
2期
27-29
,共3页
急性重度支气管哮喘%持续性血液滤过
急性重度支氣管哮喘%持續性血液濾過
급성중도지기관효천%지속성혈액려과
Acute severe bronchial asthma%Continuous hemofiltration
目的 探讨持续性血液滤过在急性重度支气管哮喘患者治疗中的效果.方法 以我院重症监护病房于2011年1至12月收治的26例急性重度支气管哮喘患者为对照组[男11例,女15例,年龄38 ～ 76岁,平均(52±19)岁],进行呼吸机辅助呼吸的同时给予糖皮质激素、β2受体兴奋剂、氨茶碱、祛痰镇咳、解痉平喘、维持水电解质酸碱平衡、补液等综合治疗.另以我院重症监护病房于2012年1月至2013年1月收治的38例急性重度支气管哮喘患者为试验组[男17例,女21例,年龄35～81岁,平均(57±20)岁],在对照组治疗的基础上联合持续性血液滤过治疗.比较两组患者机械通气时间、平均住院时间、死亡率、平均存活时间及住院费用.采用t检验和卡方检验进行数据统计.结果 与对照组相比,试验组患者机械通气时间[(2.8±0.9)vs(5.2±1.8)d]和平均住院时间[(5.8±1.2)vs(12.6±3.3)d]明显缩短,死亡率显著降低(7.89％vs 23.08％),平均存活时间明显延长[(22.9±5.9)vs(13.6±2.2)d],差异具有统计学意义(均P＜0.05).两组平均住院费用差异无统计学意义[(32 177±3129)vs(30992±2893)元,P＞0.05].结论 持续性血液滤过对急性重度支气管哮喘患者疗效显著.
目的 探討持續性血液濾過在急性重度支氣管哮喘患者治療中的效果.方法 以我院重癥鑑護病房于2011年1至12月收治的26例急性重度支氣管哮喘患者為對照組[男11例,女15例,年齡38 ～ 76歲,平均(52±19)歲],進行呼吸機輔助呼吸的同時給予糖皮質激素、β2受體興奮劑、氨茶堿、祛痰鎮咳、解痙平喘、維持水電解質痠堿平衡、補液等綜閤治療.另以我院重癥鑑護病房于2012年1月至2013年1月收治的38例急性重度支氣管哮喘患者為試驗組[男17例,女21例,年齡35～81歲,平均(57±20)歲],在對照組治療的基礎上聯閤持續性血液濾過治療.比較兩組患者機械通氣時間、平均住院時間、死亡率、平均存活時間及住院費用.採用t檢驗和卡方檢驗進行數據統計.結果 與對照組相比,試驗組患者機械通氣時間[(2.8±0.9)vs(5.2±1.8)d]和平均住院時間[(5.8±1.2)vs(12.6±3.3)d]明顯縮短,死亡率顯著降低(7.89％vs 23.08％),平均存活時間明顯延長[(22.9±5.9)vs(13.6±2.2)d],差異具有統計學意義(均P＜0.05).兩組平均住院費用差異無統計學意義[(32 177±3129)vs(30992±2893)元,P＞0.05].結論 持續性血液濾過對急性重度支氣管哮喘患者療效顯著.
목적 탐토지속성혈액려과재급성중도지기관효천환자치료중적효과.방법 이아원중증감호병방우2011년1지12월수치적26례급성중도지기관효천환자위대조조[남11례,녀15례,년령38 ～ 76세,평균(52±19)세],진행호흡궤보조호흡적동시급여당피질격소、β2수체흥강제、안다감、거담진해、해경평천、유지수전해질산감평형、보액등종합치료.령이아원중증감호병방우2012년1월지2013년1월수치적38례급성중도지기관효천환자위시험조[남17례,녀21례,년령35～81세,평균(57±20)세],재대조조치료적기출상연합지속성혈액려과치료.비교량조환자궤계통기시간、평균주원시간、사망솔、평균존활시간급주원비용.채용t검험화잡방검험진행수거통계.결과 여대조조상비,시험조환자궤계통기시간[(2.8±0.9)vs(5.2±1.8)d]화평균주원시간[(5.8±1.2)vs(12.6±3.3)d]명현축단,사망솔현저강저(7.89％vs 23.08％),평균존활시간명현연장[(22.9±5.9)vs(13.6±2.2)d],차이구유통계학의의(균P＜0.05).량조평균주원비용차이무통계학의의[(32 177±3129)vs(30992±2893)원,P＞0.05].결론 지속성혈액려과대급성중도지기관효천환자료효현저.
Objective To investigate the effect of continuous veno-venous hemofiltration (CVVH) on patients with acute severe bronchial asthma.Methods Twenty-six patients with acute severe bronchial asthma who were treated at our intensive care unit from January to December 2011 were enrolled as the control group (male 11,female 12,average age (52 ± 19) years old).The subjects in this group received mechanical ventilation,glucocorticoid,β2 receptor agonist,aminophylline,expectorant,antispasmodic medication and rehydration therapy.Another 38 adults with acute severe bronchial asthina who were treated at our intensive care unit during January 2012 and January 2013 were served as study group (male 17,female 21,average age (57 ± 20) years old),and were assigned to undergo CVVH combined with routine therapy.Mechanical ventilation duration,mean hospital stay,mortality,average survival time and hospitalization expenses were compared between the two groups.Student's t test or Chi-square test were used for data analysis.Results In comparison with the control group,mechanical ventilation duration ((2.8 ± 0.9) vs (5.2±1.8) d),average hospitalization ((5.8± 1.2) vs (12.6± 3.3) d),mortality (7.89％ vs 23.08％),average survival time ((22.9 ± 5.9) vs (13.6 ± 2.2) d) were significantly improved (all P ＜0.05).No difference in cost of hospitalization was found between the two groups (P ＞ 0.05).Conctusion CVVH may be proven to have therapeutic effect on patients with obvious acute severe bronchial asthma.
