中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
28期
29-30
,共2页
桥本病%甲状腺功能亢进%普萘洛尔%疗效
橋本病%甲狀腺功能亢進%普萘洛爾%療效
교본병%갑상선공능항진%보내락이%료효
Hashimoto’s disease%Hyperthyroidism%Propranolol%Efficacy
目的：探讨普萘洛尔治疗桥本病伴发甲状腺功能亢进的临床疗效。方法：将80例桥本病伴发甲状腺功能亢进住院患者随机分为观察组和对照组，每组40例。对照组采用抗甲状腺药物治疗，观察组采用普萘洛尔治疗，比较两组患者的治疗效果。结果：观察组患者甲状腺症状及血清学指标恢复情况明显优于对照组，差异有统计学意义(P<0.05)。观察组患者治疗总有效率为87.5%，对照组患者治疗总有效率为72.5%，差异有统计学意义(P<0.05)。观察组患者在治疗期间无一例患者出现并发症，对照组患者有5例患者出现粒细胞减少，发生率为12.5%，两组比较差异有统计学意义(P<0.05)。结论：普萘洛尔治疗桥本病伴发甲状腺功能亢进临床效果佳，并发症少，安全有效，值得临床推广应用。
目的：探討普萘洛爾治療橋本病伴髮甲狀腺功能亢進的臨床療效。方法：將80例橋本病伴髮甲狀腺功能亢進住院患者隨機分為觀察組和對照組，每組40例。對照組採用抗甲狀腺藥物治療，觀察組採用普萘洛爾治療，比較兩組患者的治療效果。結果：觀察組患者甲狀腺癥狀及血清學指標恢複情況明顯優于對照組，差異有統計學意義(P<0.05)。觀察組患者治療總有效率為87.5%，對照組患者治療總有效率為72.5%，差異有統計學意義(P<0.05)。觀察組患者在治療期間無一例患者齣現併髮癥，對照組患者有5例患者齣現粒細胞減少，髮生率為12.5%，兩組比較差異有統計學意義(P<0.05)。結論：普萘洛爾治療橋本病伴髮甲狀腺功能亢進臨床效果佳，併髮癥少，安全有效，值得臨床推廣應用。
목적：탐토보내락이치료교본병반발갑상선공능항진적림상료효。방법：장80례교본병반발갑상선공능항진주원환자수궤분위관찰조화대조조，매조40례。대조조채용항갑상선약물치료，관찰조채용보내락이치료，비교량조환자적치료효과。결과：관찰조환자갑상선증상급혈청학지표회복정황명현우우대조조，차이유통계학의의(P<0.05)。관찰조환자치료총유효솔위87.5%，대조조환자치료총유효솔위72.5%，차이유통계학의의(P<0.05)。관찰조환자재치료기간무일례환자출현병발증，대조조환자유5례환자출현립세포감소，발생솔위12.5%，량조비교차이유통계학의의(P<0.05)。결론：보내락이치료교본병반발갑상선공능항진림상효과가，병발증소，안전유효，치득림상추엄응용。
Objective:To evaluate the clinical efficacy of Propranolol in the treatmeng of Hashimoto’s disease associated with hyperthyroidism.Method:80 cases of Hashimoto’s disease associated with hyperthyroidism patients were randomly divided into two groups,40 cases in each group.The control group treated with antithyroid drug,the observation group treated with Propranolol,the curative effect of two groups were compared.Result:The thyroid symptoms and serological indicator restoration of the observation group were significantly better than the control group,the differences were statistically significant(P<0.05).The total effective rate of the observation group was 87.5%,the control group was 72.5%,the difference was statistically significant(P<0.05).The observation group patients in the treatment period with no complications,the control group had 5 cases with neutropenia,the occurrence rate was 12.5%,two groups had statistical significance difference(P<0.05).Conclusion:Hashimoto’s disease associated with hyperthyroidism treated with Propranolol has a good clinical effect,fewer complications,is safe and effective,it is worthy of clinical popularization and application.
