CAJ | 학술논문

目的：探讨急性痛风性关节炎与血尿酸及尿酸盐结晶之间的关系。方法：回顾性分析75例急性痛风性关节炎患者的一般资料、血尿酸值、尿酸盐结晶沉积部位计数；根据性别分为男女两组、根据血尿酸水平分为高血尿酸组和正常血尿酸组，采用SPSS 19.0统计软件进行统计分析。结果：年龄与血尿酸水平、尿酸盐结晶沉积部位计数均无相关性（P＞0.05）；尿酸盐结晶沉积部位计数与病程、血尿酸水平呈正相关(P＜0.05)；男性组血尿酸值（405.18±132.21）μmol/L，尿酸盐沉积部位（37.45±17.14）个，女性组血尿酸值（288.50±57.21）μmol/L，尿酸盐沉积部位（23.19±12.80）个，均存在差异(P＜0.05)；高血尿酸组尿酸盐结晶沉积部位（34.64±18.19）个，正常组尿酸盐结晶沉积部位（31.44±16.62）个，两组间无差异(P＞0.05)。结论：急性痛风性关节炎发作是以尿酸盐结晶存在为基础，其发作期血尿酸值不一定高，尿酸盐结晶沉积部位计数与血尿酸呈正相关，但两者关系有待进一步研究。
목적：탐토급성통풍성관절염여혈뇨산급뇨산염결정지간적관계。방법：회고성분석75례급성통풍성관절염환자적일반자료、혈뇨산치、뇨산염결정침적부위계수；근거성별분위남녀량조、근거혈뇨산수평분위고혈뇨산조화정상혈뇨산조，채용SPSS 19.0통계연건진행통계분석。결과：년령여혈뇨산수평、뇨산염결정침적부위계수균무상관성（P＞0.05）；뇨산염결정침적부위계수여병정、혈뇨산수평정정상관(P＜0.05)；남성조혈뇨산치（405.18±132.21）μmol/L，뇨산염침적부위（37.45±17.14）개，녀성조혈뇨산치（288.50±57.21）μmol/L，뇨산염침적부위（23.19±12.80）개，균존재차이(P＜0.05)；고혈뇨산조뇨산염결정침적부위（34.64±18.19）개，정상조뇨산염결정침적부위（31.44±16.62）개，량조간무차이(P＞0.05)。결론：급성통풍성관절염발작시이뇨산염결정존재위기출，기발작기혈뇨산치불일정고，뇨산염결정침적부위계수여혈뇨산정정상관，단량자관계유대진일보연구。
Objective To explore the relationship of acute gouty arthritis with uric acid and urate crystals. Methods A retrospective analysis of 75 cases of acute gouty arthritis of general information, uric acid, urate crystal deposition site counts was made. Men and women were separately divided into two groups, basing on the blood uric acid level divided into high uric acid group and normal uric acid group, using SPSS 19.0 statistical software for statistical analysis. Results Age and uric acid, urate crystal deposition site counts were not corre-lated(P>0.05); urate crystal deposition site counts were positively correlated with the duration and with serum uric acid levels (P<0.05). In the male group uric acid showed (405.18±132.21) μmol/L, urate crystal deposition site counts were (37.45±17.14), while in the female group uric acid (288.50±57.21) μmol/L, urate crystal deposi-tion site counts (23.19 ± 12.80), with significant differences (P<0.05) According to uric acid groups, urate crys-tal deposition site were counts of high uric acid group (34.64 ± 18.19), and normal uric acid group (31.44 ± 16.62) , with no differences (P>0.05). Conclusion Acute gouty arthritis attack is based on the presence of urate crystals, their attack is not necessarily with high uric acid, urate crystal deposition site counts and uric ac-id are positively correlated, but the relationship needs further study.