颈腰痛杂志
頸腰痛雜誌
경요통잡지
2014年
5期
432-435
,共4页
鞠建庆%李运伦%杨雯晴%张世君
鞠建慶%李運倫%楊雯晴%張世君
국건경%리운륜%양문청%장세군
心房颤动%中药复方%数据挖掘%关联规则%用药规律
心房顫動%中藥複方%數據挖掘%關聯規則%用藥規律
심방전동%중약복방%수거알굴%관련규칙%용약규률
atrial fibrillation%compound herbal formulas%data mining%association rules%medication rules
目的：探索治疗心房颤动中药复方的用药规律。方法：筛选临床研究文献中治疗心房颤动的中药复方，应用频数分析和关联规则算法，对中药复方进行数据挖掘，探讨其核心药物及配伍规律。结果：共筛选中药复方119首，核心药物34味，药对配伍规则20条，药组配伍规则24条，其中炙甘草、麦冬、丹参、五味子、黄芪、当归等为常用核心药物，麦冬-五味子、龙骨-牡蛎、炒酸枣仁-柏子仁、川芎-红花、麦冬-五味子-丹参-炙甘草等为常用配伍组合，苦参、延胡索、甘松为常用抗心律失常中药。结论：益气养阴、安神定志、活血化瘀和专病专药为治疗心房颤动的基本用药规律。
目的：探索治療心房顫動中藥複方的用藥規律。方法：篩選臨床研究文獻中治療心房顫動的中藥複方，應用頻數分析和關聯規則算法，對中藥複方進行數據挖掘，探討其覈心藥物及配伍規律。結果：共篩選中藥複方119首，覈心藥物34味，藥對配伍規則20條，藥組配伍規則24條，其中炙甘草、麥鼕、丹參、五味子、黃芪、噹歸等為常用覈心藥物，麥鼕-五味子、龍骨-牡蠣、炒痠棘仁-柏子仁、川芎-紅花、麥鼕-五味子-丹參-炙甘草等為常用配伍組閤，苦參、延鬍索、甘鬆為常用抗心律失常中藥。結論：益氣養陰、安神定誌、活血化瘀和專病專藥為治療心房顫動的基本用藥規律。
목적：탐색치료심방전동중약복방적용약규률。방법：사선림상연구문헌중치료심방전동적중약복방，응용빈수분석화관련규칙산법，대중약복방진행수거알굴，탐토기핵심약물급배오규률。결과：공사선중약복방119수，핵심약물34미，약대배오규칙20조，약조배오규칙24조，기중자감초、맥동、단삼、오미자、황기、당귀등위상용핵심약물，맥동-오미자、용골-모려、초산조인-백자인、천궁-홍화、맥동-오미자-단삼-자감초등위상용배오조합，고삼、연호색、감송위상용항심률실상중약。결론：익기양음、안신정지、활혈화어화전병전약위치료심방전동적기본용약규률。
Objective:To explore the medication rules of formulas in treating atrial fibrillation by data mining. Methods:The formulas in treating atrial fibrillation from modern clinical literatures were selected.The data were analyzed by frequency statistics and association rules to find out the medication rules. Results:Total 119 compound herbal formulas were studied. Total 34 frequently used herbs ,20 frequently used herb-pairs and 24 frequently used herb-groups were found. Prepared liquoric root,radix ophiopogonis,the root of red-rooted salvia,schisandra chinensis,astragalus membranaceus and angelica sinenisis were the top frequently-used herbs. Radix ophiopogonis-schisandra chinensis,OsDraconis-concha ostreae,Fry zizyphus jujube benevolence-semen boitae,Ligusticum wallichii-Carthamus tinctorius,radix ophiopogonis-schisandra chinensis-the root of red-rooted salvia-prepared liquoric root were the top frequently-used herb-pairs and herb-groups. Radix sophorae flavescentis-corydalis tuber-rhizoma nardostachyos were the frequently-used antiarrhythmic herbs. Conclusion:Benefiting Qi and nourishing Yin,tranquilizing the mind,promoting blood circulation for removing blood stasis and using special antiarrhythmic herbs were the common medication rules for treating atrial fibrillation.
