CAJ | 학술논문

目的：评价一叶抗流感胶囊的药效作用。方法通过大鼠酵母致热实验观察其解热作用；热板法和扭体法观察其镇痛作用；小鼠腹腔注射醋酸致毛细血管通透性增高实验观察其抗炎作用。结果高、中剂量组能明显抑制的酵母所致大鼠体温升高、降低小鼠的扭体次数和延长1h热刺痛引起的痛阈值，一叶抗流感胶囊还能明显的抑制醋酸所致毛细血管通透性的增加。结论一叶抗流感胶囊具有良好的解热、镇痛和抗炎的作用。
목적：평개일협항류감효낭적약효작용。방법통과대서효모치열실험관찰기해열작용；열판법화뉴체법관찰기진통작용；소서복강주사작산치모세혈관통투성증고실험관찰기항염작용。결과고、중제량조능명현억제적효모소치대서체온승고、강저소서적뉴체차수화연장1h열자통인기적통역치，일협항류감효낭환능명현적억제작산소치모세혈관통투성적증가。결론일협항류감효낭구유량호적해열、진통화항염적작용。
Objective To evaluate the pharmacodynamic effects of Yiye anti-influenza capsules (YYAFC). Methods The relieving fever effect was observed on Saccharomyces siccum induced fever model of rats; the analgesic effect was investigated by hot plate method and body twist method; the anti-inflammatory effect was observed by the capillary permeability augmentation of mice induced by acetic acid. Results High-dose and medial-dose of YYAFC could significantly decrease the raised body temperature caused by Saccharomyces siccum in rats, depress the torsion body of mice and increased the pain thresholds for 1 hour (P<0.05). It also could significantly inhibit capillary permeability augmentation caused by acetic acid in mice. Conclusion YYAFC has better effects on relieving fever, analgesia and anti-inflammation.