实用癌症杂志
實用癌癥雜誌
실용암증잡지
THE PRACTICAL JOURNAL OF CANCER
2014年
9期
1118-1120
,共3页
艾秀清%韩有溪%木克代斯·拜克提亚尔%木妮热·木沙江
艾秀清%韓有溪%木剋代斯·拜剋提亞爾%木妮熱·木沙江
애수청%한유계%목극대사·배극제아이%목니열·목사강
乳腺癌%复发%转移%相关因素
乳腺癌%複髮%轉移%相關因素
유선암%복발%전이%상관인소
Breast cancer%Recurrence%Metastasis%Related factors
目的：探讨乳腺癌术后复发和转移的相关因素。方法137例乳腺癌术后患者，将术后复发转移的35例作为A组，102例未发生复发转移者作为B组。收集两组患者临床资料并进行对比，通过多因素Logistic回归分析乳腺癌复发和转移的相关因素。结果年龄＜40岁患者的复发转移率为47．83％，显著高于年龄≥40岁患者的（P＜0．05）；肿瘤直径＞5 cm患者的复发转移率为72．73％，显著高于肿瘤直径＜2 cm患者的（P＜0．05）；淋巴结转移数目1～3个患者的复发转移率为34．15％，淋巴结转移数目＞3个患者的复发转移率为50．00％，均显著高于无淋巴结转移患者的（ P＜0．05）；CA15-3阳性患者复发转移率为38．71％，显著高于CA15-3阴性患者的（P＜0．05）。结论年龄＜40岁、肿瘤直径大、淋巴结转移数目多、CA15-3阳性是乳腺癌复发转移的危险因素，临床上应加强监测危险因素，强化术后放疗的抗肿瘤措施，以降低乳腺癌术后复发和转移的发生率。
目的：探討乳腺癌術後複髮和轉移的相關因素。方法137例乳腺癌術後患者，將術後複髮轉移的35例作為A組，102例未髮生複髮轉移者作為B組。收集兩組患者臨床資料併進行對比，通過多因素Logistic迴歸分析乳腺癌複髮和轉移的相關因素。結果年齡＜40歲患者的複髮轉移率為47．83％，顯著高于年齡≥40歲患者的（P＜0．05）；腫瘤直徑＞5 cm患者的複髮轉移率為72．73％，顯著高于腫瘤直徑＜2 cm患者的（P＜0．05）；淋巴結轉移數目1～3箇患者的複髮轉移率為34．15％，淋巴結轉移數目＞3箇患者的複髮轉移率為50．00％，均顯著高于無淋巴結轉移患者的（ P＜0．05）；CA15-3暘性患者複髮轉移率為38．71％，顯著高于CA15-3陰性患者的（P＜0．05）。結論年齡＜40歲、腫瘤直徑大、淋巴結轉移數目多、CA15-3暘性是乳腺癌複髮轉移的危險因素，臨床上應加彊鑑測危險因素，彊化術後放療的抗腫瘤措施，以降低乳腺癌術後複髮和轉移的髮生率。
목적：탐토유선암술후복발화전이적상관인소。방법137례유선암술후환자，장술후복발전이적35례작위A조，102례미발생복발전이자작위B조。수집량조환자림상자료병진행대비，통과다인소Logistic회귀분석유선암복발화전이적상관인소。결과년령＜40세환자적복발전이솔위47．83％，현저고우년령≥40세환자적（P＜0．05）；종류직경＞5 cm환자적복발전이솔위72．73％，현저고우종류직경＜2 cm환자적（P＜0．05）；림파결전이수목1～3개환자적복발전이솔위34．15％，림파결전이수목＞3개환자적복발전이솔위50．00％，균현저고우무림파결전이환자적（ P＜0．05）；CA15-3양성환자복발전이솔위38．71％，현저고우CA15-3음성환자적（P＜0．05）。결론년령＜40세、종류직경대、림파결전이수목다、CA15-3양성시유선암복발전이적위험인소，림상상응가강감측위험인소，강화술후방료적항종류조시，이강저유선암술후복발화전이적발생솔。
Objective To explore the related factors of recurrence and metastasis of breast cancer .Methods The clini-cal data of 137 breast cancer patients was analyzed .35 cases of relapse and metastasis of breast cancer patients was group A ,102 cases non-relapse and metastasis of breast cancer patients was group B .The factors related to recurrence and metastasis of breast cancer were compared by multivariate logistic regression analysis .Results The recurrence and metastasis rate in patients with age under 40 was 47.83%,significantly higher than patients who were 40 or over 40(P<0.05);recurrence and metastasis rate of patients with tumor diameter >5 cm with was 72.73%,significantly higher than that of tumor diameter <2 cm ( P<0.05);the recurrence and metastasis rate of patients with 1-3 metastatic lymph nodes was 34.15%,that of patients with 3 metastatic lymph nodes was 50.00%,significantly higher than that of patients without lymphatic metastasis (P<0.05);recurrence and metastasis rate of CA15-3 positive patients was 38.71%,significantly higher than that of CA15-3 negative patients (P<0.05).Conclusion Under 40,the large diameter of the tumor ,larger number of lymph node metastasis ,CA15-3 positive are risk factors for relapse and metastasis of breast cancer .Monitoring and postoperative anti-tumor measures should be strengthened in clinic ,in order to re-duce recurrence and metastases of breast cancer .
