CAJ | 학술논문

目的：探讨类风湿性关节炎( RA)患者关节液中IL-17的含量与关节炎症损伤的相关性，为研究RA的关节损伤机制提供科学依据.方法应用ELISA方法定量检测RA组40例和对照组40例关节液中IL-17的含量，应用t检验比较两组差异性.结果 RA组关节液中IL-17的含量显著高于对照组(P<0.01).结论 RA组关节液中具有较高的IL-17检测值，证实IL-17是RA患者关节滑膜损伤的重要因素之一.
목적：탐토류풍습성관절염( RA)환자관절액중IL-17적함량여관절염증손상적상관성，위연구RA적관절손상궤제제공과학의거.방법응용ELISA방법정량검측RA조40례화대조조40례관절액중IL-17적함량，응용t검험비교량조차이성.결과 RA조관절액중IL-17적함량현저고우대조조(P<0.01).결론 RA조관절액중구유교고적IL-17검측치，증실IL-17시RA환자관절활막손상적중요인소지일.
Objective To explore the relationship between the content of IL-17 in synovial fluid in patients with rheumatoid arthritis( RA) and the joint lesions,to provide the scientific basis for the research on mechanisms of joint lesions of RA. Methods The content of IL-17 in synovial fluid was quantitatively detected in 40 cases of RA group and 40 cases of control group by ELISA. t test was used to compare the differences between two groups. Result The content of IL-17 in synovial fluid of RA groups was significantly higher than that of the control groups(P<0. 01). Conclusion IL-17 in synovial fluid of RA group showed a higher detected value, indicating that it is one of important factors for the synovial lesions of joint in patients with rheumatoid arthritis.