CAJ | 학술논문

为研究夏枯草注射液的抗炎及抗菌作用，用二甲苯、蛋清分别造成小鼠和大鼠炎症模型来考察夏枯草注射液的抗炎作用，通过体外、体内抑菌试验来评价其抗菌作用。结果显示，夏枯草注射液能显著抑制二甲苯所致的小鼠耳肿胀和对蛋清致大鼠足跖肿胀，体外抗菌试验表明该注射液对痢疾杆菌、大肠杆菌、肺炎双球菌、溶血性链球菌有较好的抑菌作用，并对腹腔注射肺炎双球菌ATCC 27853引起小鼠死亡有保护作用。夏枯草注射液具有抗炎、抗菌作用，可为该药的临床应用与机制研究提供理论依据。
위연구하고초주사액적항염급항균작용，용이갑분、단청분별조성소서화대서염증모형래고찰하고초주사액적항염작용，통과체외、체내억균시험래평개기항균작용。결과현시，하고초주사액능현저억제이갑분소치적소서이종창화대단청치대서족척종창，체외항균시험표명해주사액대이질간균、대장간균、폐염쌍구균、용혈성련구균유교호적억균작용，병대복강주사폐염쌍구균ATCC 27853인기소서사망유보호작용。하고초주사액구유항염、항균작용，가위해약적림상응용여궤제연구제공이론의거。
In order to study the anti-inflammatory and antibacterial effect of Selfheal injection, a inflammatory model for mouse and rat was constructed by using dimethylbenzene and egg white, through the antibacterial test in vivo and in vitro to evaluate the antibacterial action. The result shows that Seaelfhl injection can inhibit the mouse ear edema induced by dimethylbenzene, and inhibit the rat foot swelling induced by egg white. Antimicrobial test in vitro shows that Seaelfhl injection has the function of inhibiting the growth of shigella dysenteriae, Escherichia coli, diplococcus pneumoniae and hemolytic streptococcus. Seaelfhl injection can also protect the mouse from death induced by diplococcus pneumoniae ATCC 27853. The result prove that Seaelfhl injection has the effect of anti-inflammatory and antibacterial, the test can provide basis for clinical practice of Seaelfhl injection.