CAJ | 학술논문

目的：探索体外受精胚胎移植取卵术前阴道冲洗溶液的选择。方法选择2010年1月～2011年1月共1265例IVF-ET/ICSI-ET患者作为A组，并在HCG日后用无菌生理盐水冲洗阴道。B组为2011年8月～2012年8月的2244例患者，在HCG日后用无菌生理盐水和0．05％醋酸氯己定（杨凌生物医药科技有限公司生产）联合进行阴道冲洗，再行取卵术。比较2组患者的正常受精率、卵裂率以及临床妊娠率。结果2组术后均无感染等症状发生，B组的正常受精率和临床妊娠率高于A组，2组卵裂率无统计学差异（P＞0．05）。结论2组冲洗溶液均能达到取卵术前阴道准备的目的。B组妊娠率更高，患者自我冲洗更方便，操作更简单，依从性更好，节省了护士的时间，工作效率得到提高。
목적：탐색체외수정배태이식취란술전음도충세용액적선택。방법선택2010년1월～2011년1월공1265례IVF-ET/ICSI-ET환자작위A조，병재HCG일후용무균생리염수충세음도。B조위2011년8월～2012년8월적2244례환자，재HCG일후용무균생리염수화0．05％작산록기정（양릉생물의약과기유한공사생산）연합진행음도충세，재행취란술。비교2조환자적정상수정솔、란렬솔이급림상임신솔。결과2조술후균무감염등증상발생，B조적정상수정솔화림상임신솔고우A조，2조란렬솔무통계학차이（P＞0．05）。결론2조충세용액균능체도취란술전음도준비적목적。B조임신솔경고，환자자아충세경방편，조작경간단，의종성경호，절성료호사적시간，공작효솔득도제고。
Objective To explore the methods of vaginal preparation before cocyte retrieval in vitro fertilization-embryo transfer.Method 1 265 patients (control group)needing vaginal preparation before cocyte retrieval in vitro fertilization-embryo transfer from Junuary 201 0 to Junuary 201 1 used sterile saline to wash the vagina before cocyte retrieval.2244 patients(intervention group)needing vaginal preparation before cocyte retrieval in vitro fertilization-embryo transfer from August 201 1 to August 201 2 used sterile saline and 0.05% chlorhexidine acetate to wash the vagina.Compare two groups’the normal fertilization rate,cleavage rate and pregnancy rate.Results There were no significantly sta-tistical difference on cleavage rate between the two group.But there were higher normal fertilization rate and pregnancy rate in intervention group (P<0.05).Conclusion Two methods can be used to rinse the vaguna before cocyte retrieval.The method of using sterile saline and 0.05%chlorhexidine acetate has higher pregnancy rate and better compliance,which help save nurses’time and improve the work efficiency.