CAJ | 학술논문

目的：探讨广州地区健康人群和癌症患者血清肿瘤特异性生长因子（TSGF）水平。方法对该院2012年7月至2013年6月6615例健康体检者及287例恶性肿瘤患者进行血清TSGF检测。结果＞40～50岁女性健康体检者TSGF水平及阳性率较高；男性健康体检者随着年龄增长，TSGF水平及阳性率都有升高趋势。肺癌、肝癌及消化系统恶性肿瘤患者 TSGF水平明显高于健康体检者（P＜0．01）；而生殖系统恶性肿瘤患者 TSGF水平和阳性率与健康体检者比较，差异无统计学意义（P＞0．05）。结论将TSGF作为健康体检的筛查指标，对于某些恶性肿瘤的早期筛查具有重要意义；TSGF检测应根据不同年龄、不同性别制订相应的参考范围。
목적：탐토엄주지구건강인군화암증환자혈청종류특이성생장인자（TSGF）수평。방법대해원2012년7월지2013년6월6615례건강체검자급287례악성종류환자진행혈청TSGF검측。결과＞40～50세녀성건강체검자TSGF수평급양성솔교고；남성건강체검자수착년령증장，TSGF수평급양성솔도유승고추세。폐암、간암급소화계통악성종류환자 TSGF수평명현고우건강체검자（P＜0．01）；이생식계통악성종류환자 TSGF수평화양성솔여건강체검자비교，차이무통계학의의（P＞0．05）。결론장TSGF작위건강체검적사사지표，대우모사악성종류적조기사사구유중요의의；TSGF검측응근거불동년령、불동성별제정상응적삼고범위。
Objective To investigate the results of tumor specific growth factor(TSGF) levels in in healthy people and cancer patients in Guangzhou areas .Methods The serum TSGF levels of 6 615 health check-up receivers and 287 patients with cancer in the hospital from July 2012 to June 2013 were detected .Results In health check-up receivers ,the level and positive rate of TSGF were higher in >40-50 age women .The level and positive rate of TSGF in men were increased with age .The levels of TSGF in pa-tients with lung cancer ,liver cancer and digestive system tumor were higher than that in health check-up receivers(P<0 .01) ,but there has no statistically difference between genital system cancer patients and healthy check-up receivers(P>0 .05) .Conclusion Performing TSGF test in health examination is great significance to the early diagnosis of malignant tumors .The reference value range of TSGF should be set according to different gender and age .