CAJ | 학술논문

目的：分析113例病灶分泌物真菌分布及药物敏感试验结果，更好地为临床提供确切的治疗药物。方法收集113例真菌感染病灶分泌物标本，对其进行真菌鉴定及药物敏感试验。结果113例真菌感染病灶分泌物标本中，白色念珠菌75株（66．4％），都柏林念珠菌29株（26．7％），近平滑念珠菌6例（5．3％），克柔念珠菌3例（2．7％）。5-氟胞嘧啶和两性霉素B对白色念珠菌的敏感度较高，分别为94．7％和97．3％；两性霉素B对都柏林念珠菌的敏感率为93．1％；伏立康唑和两性霉素B对近平滑念珠菌的敏感率均为83．3％；5-氟胞嘧啶和两性霉素B对克柔念珠菌的敏感率均为100．0％。结论加强用药前病灶分泌物的真菌培养和药物敏感试验，合理应用抗菌药物有助于患者的治疗。
목적：분석113례병조분비물진균분포급약물민감시험결과，경호지위림상제공학절적치료약물。방법수집113례진균감염병조분비물표본，대기진행진균감정급약물민감시험。결과113례진균감염병조분비물표본중，백색념주균75주（66．4％），도백림념주균29주（26．7％），근평활념주균6례（5．3％），극유념주균3례（2．7％）。5-불포밀정화량성매소B대백색념주균적민감도교고，분별위94．7％화97．3％；량성매소B대도백림념주균적민감솔위93．1％；복립강서화량성매소B대근평활념주균적민감솔균위83．3％；5-불포밀정화량성매소B대극유념주균적민감솔균위100．0％。결론가강용약전병조분비물적진균배양화약물민감시험，합리응용항균약물유조우환자적치료。
Objective To analyze the fungal distribution and drug sensitivity analysis in 113 cases of lesion secretions .Methods Identification of fungi and drug sensitive test were done in 113 cases of lesion secretions .Results Among the 113 cases of lesion se-cretions ,there were Candida albicans 75 cases(66 .4% ) ,Candida dublin 29 cases(26 .7% ) ,Candida parapsilosis 6 cases(5 .3% ) , Candida krusei 3 cases(2 .7% ) .For Candida albicans ,the drug sensitive rates of 5-fluorocytosine and amphotericin B were 94 .7%and 97 .3% respectively .For Candida dublin ,the drug sensitive rate of amphotericin B was 93 .1% .For Candida parapsilosis ,the drug sensitive rates of voriconazole and amphotericin B were both 83 .3% .For Candida krusei ,the drug sensitive rates of 5-fluoro-cytosine and amphotericin B were both 100 .0% .Conclusion Strengthening the fungal distribution and drug sensitivity analysis be-fore treatment in fungal lesion secretions may provide direction for the clinical treatments .