CAJ | 학술논문

目的：探讨常规浆膜腔积液中淋巴瘤细胞形态学诊断效果。方法临床抽取浆膜腔积液立即送检，行瑞氏-姬姆萨染色，镜检。分析浆膜腔积液中恶性淋巴瘤的细胞形态特征。结果1440例患者的浆膜腔积液中检测到淋巴瘤细胞62例，灵敏度89．55％，特异性99．85％，阳性预测值96．77％，阴性预测值99．49％，总有效率99．38％。淋巴瘤细胞多见于胸腔积液（46例），其次为腹腔积液（18例），心包腔积液最少（3例）。细胞涂片镜检发现，淋巴瘤细胞形态可分为空泡形态、大细胞形态、小细胞形态、不规则形态。结论常规浆膜腔积液中淋巴瘤细胞形态特征性强，对于临床辅助诊断具有重要的指导意义。
목적：탐토상규장막강적액중림파류세포형태학진단효과。방법림상추취장막강적액립즉송검，행서씨-희모살염색，경검。분석장막강적액중악성림파류적세포형태특정。결과1440례환자적장막강적액중검측도림파류세포62례，령민도89．55％，특이성99．85％，양성예측치96．77％，음성예측치99．49％，총유효솔99．38％。림파류세포다견우흉강적액（46례），기차위복강적액（18례），심포강적액최소（3례）。세포도편경검발현，림파류세포형태가분위공포형태、대세포형태、소세포형태、불규칙형태。결론상규장막강적액중림파류세포형태특정성강，대우림상보조진단구유중요적지도의의。
Objective To study the effect of cytomorphological analyses of malignant lymphomas in serous effusions .Methods Aspirating serous effusion were analyzed immediately ,then centrifugated ,stained with Wright-Giemsa ,and observed under micro-scope .The cytomorphological characteristics of lymphomas in serous effusions was analysed .Results 62 cases of malignant lym-phomas were found in 1 440 cases of the serous effusion .The diagnosis efficiencies of lymphomas were 89 .55% for sensitivity , 99 .85% for specificity ,96 .77% for positive expectant value ,99 .49% for negative expectant value and 99 .38% for total effective rate .Lymphoma cells were watched more in pleural effusion(46 cases) than in ascites(18 cases) and pericardial effusion(3 cases) . Cytomorphology of lymphomas included vacuoles ,large cells ,small cells and irregular cells .Conclusion The cytomorphological analysis of malignant lymphomas in serous effusion has an instructive significance to the clinical auxiliary diagnosis .