医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2014年
19期
2538-2540
,共3页
宫颈腺癌%免疫组织化学%原发性肿瘤%继发性肿瘤
宮頸腺癌%免疫組織化學%原髮性腫瘤%繼髮性腫瘤
궁경선암%면역조직화학%원발성종류%계발성종류
Cervical adenocarcinoma%Immunohistochemistry%Primary tumor%Secondary tumor
目的：探讨宫颈腺癌的临床病理特点及鉴别诊断。方法：回顾成都市第一人民医院病理科2012年5月-2014年5月35923例组织学标本中诊断的15例宫颈腺癌，结合免疫组化分析。结果：在35923例组织学标本中，诊断宫颈腺癌15例，占0．04％。15宫颈腺癌中，原发性宫颈腺癌8例，占53％。继发性宫颈腺癌7例，占47％。原发性宫颈腺癌组织学亚型包括：宫颈性腺癌5例，子宫内膜样腺癌2例，绒毛管状腺型1例；继发性宫颈腺癌包括：肠型腺癌2例及子宫内膜样腺癌5例，其免疫组化染色ER（＋）、Vim（＋）、CEA 3例（-），2例灶性（＋）。结论：与宫颈鳞癌相比，宫颈腺癌少见，不易早期发现。临床及免疫组化在宫颈腺癌原发性及继发性的鉴别中有重要意义。
目的：探討宮頸腺癌的臨床病理特點及鑒彆診斷。方法：迴顧成都市第一人民醫院病理科2012年5月-2014年5月35923例組織學標本中診斷的15例宮頸腺癌，結閤免疫組化分析。結果：在35923例組織學標本中，診斷宮頸腺癌15例，佔0．04％。15宮頸腺癌中，原髮性宮頸腺癌8例，佔53％。繼髮性宮頸腺癌7例，佔47％。原髮性宮頸腺癌組織學亞型包括：宮頸性腺癌5例，子宮內膜樣腺癌2例，絨毛管狀腺型1例；繼髮性宮頸腺癌包括：腸型腺癌2例及子宮內膜樣腺癌5例，其免疫組化染色ER（＋）、Vim（＋）、CEA 3例（-），2例竈性（＋）。結論：與宮頸鱗癌相比，宮頸腺癌少見，不易早期髮現。臨床及免疫組化在宮頸腺癌原髮性及繼髮性的鑒彆中有重要意義。
목적：탐토궁경선암적림상병리특점급감별진단。방법：회고성도시제일인민의원병이과2012년5월-2014년5월35923례조직학표본중진단적15례궁경선암，결합면역조화분석。결과：재35923례조직학표본중，진단궁경선암15례，점0．04％。15궁경선암중，원발성궁경선암8례，점53％。계발성궁경선암7례，점47％。원발성궁경선암조직학아형포괄：궁경성선암5례，자궁내막양선암2례，융모관상선형1례；계발성궁경선암포괄：장형선암2례급자궁내막양선암5례，기면역조화염색ER（＋）、Vim（＋）、CEA 3례（-），2례조성（＋）。결론：여궁경린암상비，궁경선암소견，불역조기발현。림상급면역조화재궁경선암원발성급계발성적감별중유중요의의。
Objective:To investigate the clinicopathologic characteristics ,diagnosis and differential diagnosis of cervical adenocarcinoma .Methods:Clinicopathologic and immunohistochemical data of 15 cases of endocervical adenocarcinoma , diagnosed among 35 923 patients at Chengdu NO .1 people’s hospital pathology department during May 2012 and May 2014 were retrospectively reviewed .Results:The prevalence of cervical adenocarcinoma was 15 of 35 923 (0.04% ) .A-mong 15 cervical adenocarcinomas ,the primary and the secondary tumors were 8(53% ) and 7(47% ) ,respectively .His-topathologically ,the subtype of primary cervical adenocarcinomas were of mucinous endocervical type 5 cases ,of endo-metrioid type 2 cases ,and of villoglandular type 1 case .The secondary cervical adenocarcinomas comprised intestinal type 2 cases and endometrioid type 5 cases ,in which both ER and Vim staining were positive ,and CEA staining was negative in 3 cases and focally positive in 2 cases .Conclusion:Compared with cervical squamous carcinoma ,adenocarci-noma is uncommon ,with difficulties in early detection .Clinic and immunohistochemical data are useful for distinguis-hing primary from secondary cervical adenocarcinoma.
