CAJ | 학술논문

目的：观察钽棒植入联合自体骨髓间充质干细胞移植治疗早期股骨头缺血性坏死的临床疗效。方法：对27例ARCOⅠ、Ⅱ期的ANFH患者采用股骨头髓芯减压后植入钽棒并联合自体骨髓间充质干细胞移植。结果：所有患者经过7～24个月（平均13个月）的随访，关节疼痛基本消失，活动范围接近或恢复正常，除2例患者进展为ARCOⅢ期外，其余股骨头均无塌陷，影像学检查结果示股骨头囊性变消失，Harris评分由术前的（54．2±7．1）分提高到术后（83．9±8．6）分。结论：钽棒植入联合自体骨髓间充质干细胞移植治疗早期股骨头缺血性坏死，具有创伤小、疗效确切等优点，近期临床疗效良好。
목적：관찰단봉식입연합자체골수간충질간세포이식치료조기고골두결혈성배사적림상료효。방법：대27례ARCOⅠ、Ⅱ기적ANFH환자채용고골두수심감압후식입단봉병연합자체골수간충질간세포이식。결과：소유환자경과7～24개월（평균13개월）적수방，관절동통기본소실，활동범위접근혹회복정상，제2례환자진전위ARCOⅢ기외，기여고골두균무탑함，영상학검사결과시고골두낭성변소실，Harris평분유술전적（54．2±7．1）분제고도술후（83．9±8．6）분。결론：단봉식입연합자체골수간충질간세포이식치료조기고골두결혈성배사，구유창상소、료효학절등우점，근기림상료효량호。
Objective:To study the effects of implantation of tantalum rod and transplantation of autologous bone mar-row mesenchymal stem cells for early stage of avascular necrosis of femoral head .Methods:27 patients with avascular necrosis of femoral head in the early stage were treated with implantation of tantalum rod and transplantation of autolo-gous bone marrow mesenchymal stem cells .Results:The average period of follow-up was thirteen months (7 ~ 24 months) .Pain of all patients disappeared .The movement range of the hip joint was normal or approximate to normal . Except two cases evolved to stage of ARCOⅢ ,X-ray showed that cystic degeneration disappeared .The Harris score was 54 .2 ± 7 .1 before operation and it increased significantly to 83 .9 ± 8 .6 after operation .Conclusion:It has the ad-vantage to minimal damage of implantation of tantalum rod and transplantation of autologous bone marrow mesenchy-mal stem cells for early stage of avascular necrosis of femoral head .It is an effective way for the treatment of femoral head necrosis .The short-term efficacy is good .