CAJ | 학술논문

目的：探讨局部注射A型肉毒毒素（BTX-A）对脑卒中后痉挛性肘及手功能障碍的改善作用。方法：20例伴有上肢痉挛的患者在BTX-A 治疗前及治疗后2周、4周和12周应用改良 Ashworth量表（MAS）、Fugl-Meyer量表（FMA）、改良Barthel指数（MBI）进行评估。结果：治疗后MAS改善（P＜0．05），改善于注射后2周稳定出现，并至少维持12周。FMA、MBI与治疗前比较无显著性差异（P＞0．05）。结论：BTX-A局部注射可以改善脑卒中后上肢痉挛及部分功能。
목적：탐토국부주사A형육독독소（BTX-A）대뇌졸중후경련성주급수공능장애적개선작용。방법：20례반유상지경련적환자재BTX-A 치료전급치료후2주、4주화12주응용개량 Ashworth량표（MAS）、Fugl-Meyer량표（FMA）、개량Barthel지수（MBI）진행평고。결과：치료후MAS개선（P＜0．05），개선우주사후2주은정출현，병지소유지12주。FMA、MBI여치료전비교무현저성차이（P＞0．05）。결론：BTX-A국부주사가이개선뇌졸중후상지경련급부분공능。
Objective:To evaluate the efficacy of botulinum toxin type A (BTX-A) in the treatment of upper limb mus-cle spasticity ,especially hand function obstacle and elbow extension ,caused by stroke .Methods:Muscle tone was as-sessed using the Modified Ashworth Scale (MAS) .Other outcome measures were the Fugl-Meyer assessment(FMA) and modified Barthel lndex(MBI) .20 patients were assessed at baseline and 2 ,4 and 12 weeks after treatment .Results:The scores of MAS improved after treatment(P<0 .05) ,from 2 weeks to 12 weeks .No significant improvement was observed in FMA and MBI(P>0 .05) .Conclusion:Local BTX-A injection can reduce the spasticity ,and improve func-tion of upper limbs for stroke patients .