中国医药导报
中國醫藥導報
중국의약도보
CHINA MEDICAL HERALD
2014年
28期
39-42
,共4页
稳定期慢性阻塞性肺疾病%认知功能障碍%肺功能%血气分析
穩定期慢性阻塞性肺疾病%認知功能障礙%肺功能%血氣分析
은정기만성조새성폐질병%인지공능장애%폐공능%혈기분석
Stable chronic obstructive pulmonary disease%Cognitive dysfunction%Pulmonary function%Blood oxygen pres-sure
目的：研究稳定期慢性阻塞性肺疾病(COPD)患者的认知功能障碍。方法选择2011年1月~2013年5月在河北医科大学第一附属医院治疗的COPD患者60例及同期健康志愿者60例，分为COPD组及对照组，进行动脉血气分析、肺功能测定及认知功能测定，其中认知功能测定包括注意力、言语学习和记忆、非言语学习和记忆、前额执行功能分等17项内容，比较两组的各项认知功能差异。结果 COPD组连线测验及数字广度测验-倒背、前额执行功能(除stroop C)测验结果与对照组比较，差异有高度统计学意义(P<0.01)；COPD组数字广度测验-顺背、言语学习和记忆、即刻和延迟视觉再生测验结果与对照组比较，差异有统计学意义(P<0.05)。COPD组即刻和延迟再认、stroop C测验结果与对照组比较，差异无统计学意义(P>0.05)。结论稳定期COPD患者广泛存在认知功能障碍，尤其是注意力、前额执行功能、记忆力等功能显著降低，严重影响稳定期COPD患者的治疗效果及生活质量，加快COPD认知功能障碍的治疗及诊断指南的出台，应是广大医务工作者工作的共同目标。
目的：研究穩定期慢性阻塞性肺疾病(COPD)患者的認知功能障礙。方法選擇2011年1月~2013年5月在河北醫科大學第一附屬醫院治療的COPD患者60例及同期健康誌願者60例，分為COPD組及對照組，進行動脈血氣分析、肺功能測定及認知功能測定，其中認知功能測定包括註意力、言語學習和記憶、非言語學習和記憶、前額執行功能分等17項內容，比較兩組的各項認知功能差異。結果 COPD組連線測驗及數字廣度測驗-倒揹、前額執行功能(除stroop C)測驗結果與對照組比較，差異有高度統計學意義(P<0.01)；COPD組數字廣度測驗-順揹、言語學習和記憶、即刻和延遲視覺再生測驗結果與對照組比較，差異有統計學意義(P<0.05)。COPD組即刻和延遲再認、stroop C測驗結果與對照組比較，差異無統計學意義(P>0.05)。結論穩定期COPD患者廣汎存在認知功能障礙，尤其是註意力、前額執行功能、記憶力等功能顯著降低，嚴重影響穩定期COPD患者的治療效果及生活質量，加快COPD認知功能障礙的治療及診斷指南的齣檯，應是廣大醫務工作者工作的共同目標。
목적：연구은정기만성조새성폐질병(COPD)환자적인지공능장애。방법선택2011년1월~2013년5월재하북의과대학제일부속의원치료적COPD환자60례급동기건강지원자60례，분위COPD조급대조조，진행동맥혈기분석、폐공능측정급인지공능측정，기중인지공능측정포괄주의력、언어학습화기억、비언어학습화기억、전액집행공능분등17항내용，비교량조적각항인지공능차이。결과 COPD조련선측험급수자엄도측험-도배、전액집행공능(제stroop C)측험결과여대조조비교，차이유고도통계학의의(P<0.01)；COPD조수자엄도측험-순배、언어학습화기억、즉각화연지시각재생측험결과여대조조비교，차이유통계학의의(P<0.05)。COPD조즉각화연지재인、stroop C측험결과여대조조비교，차이무통계학의의(P>0.05)。결론은정기COPD환자엄범존재인지공능장애，우기시주의력、전액집행공능、기억력등공능현저강저，엄중영향은정기COPD환자적치료효과급생활질량，가쾌COPD인지공능장애적치료급진단지남적출태，응시엄대의무공작자공작적공동목표。
Objective To study cognitive dysfunction of patients with stable chronic obstructive pulmonary disease (COPD). Methods From January 2011 to May 2013, in the First Hospital of Hebei Medical University, 60 patients with COPD and 60 healthy volunteers at the same period were chosen and divided into the COPD group (60 cases) and the control group (60 cases), progress in arterial blood gas analysis, pulmonary function, and cognitive function score, cogni-tive functions determination including attention, verbal learning and memory, non-verbal learning and memory, execu-tive functions forehead grading 17 contents, the differences between the two groups on the cognitive function were compared. Results The results of the connection test and digit span test-recite, forehead executive function (except stroop C) test in COPD group were compared with those in the control group, the differences were statistically signifi-cant (P<0.01); the results of the digit span test-along the back, verbal learning and memory, immediate and delayed visual reproduction test in COPD group were compared with those in the control group, the differences were statistically significant (P< 0.05). The results of the immediate and delayed recognition, stroop C test in COPD group were com-pared with those in the control group, the differences were not statistically significant (P> 0.05). Conclusion Patients with stable COPD widespread cognitive dysfunction, especially attention, forehead executive function, memory and other functions significantly reduced, seriously affecting the stable COPD patient outcomes and quality of life, to accelerate the treatment of cognitive dysfunction in COPD and diagnostic guidelines the introduction is the majority of medical workers work common goal.
