吉林医学
吉林醫學
길림의학
JILIN MEDICAL JOURANL
2014年
30期
6707-6708
,共2页
胰腺肿瘤%实性假乳头状肿瘤%内分泌肿瘤
胰腺腫瘤%實性假乳頭狀腫瘤%內分泌腫瘤
이선종류%실성가유두상종류%내분비종류
Tumor of pancreas%Solid- pseudopapillary tumor%Endocrine tumor
目的：探讨胰腺实性假乳头状瘤（ SPTP ）的临床表现、病理学特征和免疫组织化学特点，提高对此病的认识。方法：对3例SPTP的临床表现、组织病理、免疫表型进行观察并复习相关文献。结果：3例SPTP中2例临床表现为上腹部不适，1例为体检偶然发现。2例发生在胰尾，1例发生在胰体尾。其中1例显微镜下可见坏死、神经血管侵犯等现象。术后随访6个月~7年，所有患者尚未发现复发及转移。结论：SPTP是少见的胰腺肿瘤，多见于年轻女性，一般无特异性临床表现。所有病变均发生囊性变，影像学检查有一定特异性。胰腺实性假乳头状肿瘤是一种少见的具有恶性潜能的胰腺肿瘤，好发于年轻女性，也见于男性。组织起因不明与胰腺内分泌肿瘤组织学特征和免疫表现有许多相似，手术切除肿瘤可治愈，预后良好，少数病例复发。病理特点以温和一致的类圆形或卵圆形细胞增生呈实性结构，并伴出血和囊性变，部分组织退变呈假乳头结构为主要组织学特征。
目的：探討胰腺實性假乳頭狀瘤（ SPTP ）的臨床錶現、病理學特徵和免疫組織化學特點，提高對此病的認識。方法：對3例SPTP的臨床錶現、組織病理、免疫錶型進行觀察併複習相關文獻。結果：3例SPTP中2例臨床錶現為上腹部不適，1例為體檢偶然髮現。2例髮生在胰尾，1例髮生在胰體尾。其中1例顯微鏡下可見壞死、神經血管侵犯等現象。術後隨訪6箇月~7年，所有患者尚未髮現複髮及轉移。結論：SPTP是少見的胰腺腫瘤，多見于年輕女性，一般無特異性臨床錶現。所有病變均髮生囊性變，影像學檢查有一定特異性。胰腺實性假乳頭狀腫瘤是一種少見的具有噁性潛能的胰腺腫瘤，好髮于年輕女性，也見于男性。組織起因不明與胰腺內分泌腫瘤組織學特徵和免疫錶現有許多相似，手術切除腫瘤可治愈，預後良好，少數病例複髮。病理特點以溫和一緻的類圓形或卵圓形細胞增生呈實性結構，併伴齣血和囊性變，部分組織退變呈假乳頭結構為主要組織學特徵。
목적：탐토이선실성가유두상류（ SPTP ）적림상표현、병이학특정화면역조직화학특점，제고대차병적인식。방법：대3례SPTP적림상표현、조직병리、면역표형진행관찰병복습상관문헌。결과：3례SPTP중2례림상표현위상복부불괄，1례위체검우연발현。2례발생재이미，1례발생재이체미。기중1례현미경하가견배사、신경혈관침범등현상。술후수방6개월~7년，소유환자상미발현복발급전이。결론：SPTP시소견적이선종류，다견우년경녀성，일반무특이성림상표현。소유병변균발생낭성변，영상학검사유일정특이성。이선실성가유두상종류시일충소견적구유악성잠능적이선종류，호발우년경녀성，야견우남성。조직기인불명여이선내분비종류조직학특정화면역표현유허다상사，수술절제종류가치유，예후량호，소수병례복발。병리특점이온화일치적류원형혹란원형세포증생정실성결구，병반출혈화낭성변，부분조직퇴변정가유두결구위주요조직학특정。
Objective To study the pancreas solid false papilloma( SPTP)of clinical manifestations,pathology features and immuno-histochemical characteristics,improve the awareness of the disease. Methods 3 cases of SPTP clinical,histopathologic and observation of the immune phenotype and review related literature. Results 3 cases of SPTP on 2 cases clinical manifestation of abdominal discomfort,1 case of a medical accident found that 2 cases occurred in pancreatic tail,1 case occurred in pancreatic tail. Including 1 case of necrosis un-der a microscope,the phenomenon such as nerve vascular invasion. Were followed up for 6 months to 7 years postoperatively,all patients have been found recurrence and metastasis. Conclusion SPTP is a rare pancreatic tumor,see more at young women,there is no specific clinical manifestations,changes are all cystic change,imaging studies have certain specificity. Pancreas solid false papillary tumor is a rare malignant potential with pancreatic tumor,good hair at young women,also found in men,the cause is unknown and pancreatic endocrine tumor histologic features and there are many similar immune performance,surgical removal of the tumor can be cured,the more good,after a few cases of recurrence. Pathological characteristics consistent with moderate class round or ovoid cell hyperplasia in solid structure,and with bleeding,and cystic change,part of the organization as the main histologic degeneration is fake nipple structure characteristics.
