中医药学报
中醫藥學報
중의약학보
ACTA CHINESE MEDICINE AND PHARMACOLOGY
2014年
5期
79-81
,共3页
牛文民%刘智斌%杨晓航%王渊
牛文民%劉智斌%楊曉航%王淵
우문민%류지빈%양효항%왕연
血管性痴呆%头皮发际区微针疗法%同型半胱氨酸
血管性癡呆%頭皮髮際區微針療法%同型半胱氨痠
혈관성치태%두피발제구미침요법%동형반광안산
Vascular dementia%Micro-acupuncture in the hairline regions of the scalp%Homocysteine
目的:探讨头皮发际区微针疗法治疗血管性痴呆( VD)的疗效。方法:80例VD患者随机分为两组。观测组用头皮发际区微针疗法,对照组用口服药物疗法。用循环酶法检测血浆同型半胱氨酸( Hcy)的浓度,采用MMSE和ADL量表评定患者的认知功能、社会活动功能及日常生活能力。结果:两组疗效比较:观测组的总有效率为62.50%,对照组的总有效率为55.00%,二者差异有显著性意义(P<0.05),治疗后两组MMSE、ADL量表评分与治疗前自身比较均有显著改善(P<0.01);治疗后,观测组的MMSE、ADL量表评分与对照组相比较改善更为明显(P<0.05);两组血浆Hcy 水平治疗后较治疗前自身比较均有显著下降( P<0.01);治疗后,观测组血浆 Hcy水平与对照组比较,下降更为明显(P<0.05)。结论:头皮发际区微针疗法对于VD患者具有确切疗效,其治疗机理与降低血浆 Hcy水平相关。
目的:探討頭皮髮際區微針療法治療血管性癡呆( VD)的療效。方法:80例VD患者隨機分為兩組。觀測組用頭皮髮際區微針療法,對照組用口服藥物療法。用循環酶法檢測血漿同型半胱氨痠( Hcy)的濃度,採用MMSE和ADL量錶評定患者的認知功能、社會活動功能及日常生活能力。結果:兩組療效比較:觀測組的總有效率為62.50%,對照組的總有效率為55.00%,二者差異有顯著性意義(P<0.05),治療後兩組MMSE、ADL量錶評分與治療前自身比較均有顯著改善(P<0.01);治療後,觀測組的MMSE、ADL量錶評分與對照組相比較改善更為明顯(P<0.05);兩組血漿Hcy 水平治療後較治療前自身比較均有顯著下降( P<0.01);治療後,觀測組血漿 Hcy水平與對照組比較,下降更為明顯(P<0.05)。結論:頭皮髮際區微針療法對于VD患者具有確切療效,其治療機理與降低血漿 Hcy水平相關。
목적:탐토두피발제구미침요법치료혈관성치태( VD)적료효。방법:80례VD환자수궤분위량조。관측조용두피발제구미침요법,대조조용구복약물요법。용순배매법검측혈장동형반광안산( Hcy)적농도,채용MMSE화ADL량표평정환자적인지공능、사회활동공능급일상생활능력。결과:량조료효비교:관측조적총유효솔위62.50%,대조조적총유효솔위55.00%,이자차이유현저성의의(P<0.05),치료후량조MMSE、ADL량표평분여치료전자신비교균유현저개선(P<0.01);치료후,관측조적MMSE、ADL량표평분여대조조상비교개선경위명현(P<0.05);량조혈장Hcy 수평치료후교치료전자신비교균유현저하강( P<0.01);치료후,관측조혈장 Hcy수평여대조조비교,하강경위명현(P<0.05)。결론:두피발제구미침요법대우VD환자구유학절료효,기치료궤리여강저혈장 Hcy수평상관。
Objective:To evaluate the efficacy of patients with vascular dementia ( VD) treated by micro-acupuncture in the hairline regions of scalp.Methods:80 cases of VD were treated by micro-acupuncture in the hairline regions of the scalp.Before and after treatment, the changes about Plasma Homocysteine ( Hcy) , MMSE and ADL rating scale were examined for evaluating patients′cognitive function and activities of daily living.Results:The effective rate of observa-tion group (62.50%)was higher than that of control group(55.00%)(P<0.05);After treatment,the MMSE and ADL scores in two groups were improved significantly(P<0.01);the MMSE and ADL scores of observation group were im-proved better than that of control group(P<0.05).After treatment ,the Hcy levels in two groups were decreased signifi-cantly(P<0.01);the Hcy levels of observation group were decreased more than that of control group (P<0.05). Conclusion:The micro-acupuncture in the hairline regions of the scalp is an effective therapy for VD and its therapeutic mechanism may be related closely to reducing Hcy levels in blood.