中医药学报
中醫藥學報
중의약학보
ACTA CHINESE MEDICINE AND PHARMACOLOGY
2014年
5期
51-53
,共3页
睑板腺功能障碍%蒸发过强型干眼%清眩润目饮
瞼闆腺功能障礙%蒸髮過彊型榦眼%清眩潤目飲
검판선공능장애%증발과강형간안%청현윤목음
Meibomian gland dysfunction%Evaporative dry eyes%Qingxuan Runmu Yin
目的：观察中药清眩润目饮治疗睑板腺功能障碍致蒸发过强型干眼的临床疗效并探讨作用机制。方法：收集我院2012年7月～2013年7月门诊就诊的60例（120眼）睑板腺功能障碍致蒸发过强型干眼患者，随机分为治疗组和对照组各30（60眼）例，治疗组给予自拟中药清眩润目饮治疗，对照组予典必殊滴眼液治疗，治疗4周，观察对比两组疗效。结果：治疗组30例（60眼）中治愈18只眼，好转38只眼，有效率93．33％。对照组30例（60眼）中治愈7只眼，好转42只眼，有效率81．67％。经统计学分析，P＜0．05有显著差异。治疗组患者经治疗后在临床症状和体征、泪液分泌、泪膜破裂时间以及角膜荧光染色方面均优于对照组（P＜0．05）。结论：自拟中药清眩润目饮治疗睑板腺功能障碍致蒸发过强型干眼的疗效优于典必殊滴眼液的疗效。
目的：觀察中藥清眩潤目飲治療瞼闆腺功能障礙緻蒸髮過彊型榦眼的臨床療效併探討作用機製。方法：收集我院2012年7月～2013年7月門診就診的60例（120眼）瞼闆腺功能障礙緻蒸髮過彊型榦眼患者，隨機分為治療組和對照組各30（60眼）例，治療組給予自擬中藥清眩潤目飲治療，對照組予典必殊滴眼液治療，治療4週，觀察對比兩組療效。結果：治療組30例（60眼）中治愈18隻眼，好轉38隻眼，有效率93．33％。對照組30例（60眼）中治愈7隻眼，好轉42隻眼，有效率81．67％。經統計學分析，P＜0．05有顯著差異。治療組患者經治療後在臨床癥狀和體徵、淚液分泌、淚膜破裂時間以及角膜熒光染色方麵均優于對照組（P＜0．05）。結論：自擬中藥清眩潤目飲治療瞼闆腺功能障礙緻蒸髮過彊型榦眼的療效優于典必殊滴眼液的療效。
목적：관찰중약청현윤목음치료검판선공능장애치증발과강형간안적림상료효병탐토작용궤제。방법：수집아원2012년7월～2013년7월문진취진적60례（120안）검판선공능장애치증발과강형간안환자，수궤분위치료조화대조조각30（60안）례，치료조급여자의중약청현윤목음치료，대조조여전필수적안액치료，치료4주，관찰대비량조료효。결과：치료조30례（60안）중치유18지안，호전38지안，유효솔93．33％。대조조30례（60안）중치유7지안，호전42지안，유효솔81．67％。경통계학분석，P＜0．05유현저차이。치료조환자경치료후재림상증상화체정、루액분비、루막파렬시간이급각막형광염색방면균우우대조조（P＜0．05）。결론：자의중약청현윤목음치료검판선공능장애치증발과강형간안적료효우우전필수적안액적료효。
Objective:To observe the clinical effects of traditional Chinese medicine Qingxuan Runmu Yin on meibomian gland dysfunction inducing the evaporative dry eyes and to discuss the mechanism.Methods:Select 60 outpatients(120 eyes) diagnosed as chronic blepharitis from July,2012 to July,2013,and randomize outpatients into a treatment group and a control group,with 30 cases(60 eyes) in each group.The treatment group was treated with traditional Chinese medicine Qingxuan Runmu Yin.The control group was treated with Tobramycin and Dexamethasone eye drops alone for 4 weeks.Observe the effect of two groups and compare them.Results:18 of 60 eyes were cured and 38 eyes were in-proved in the treatment group,and the effective rate was 93 .33%.There were 7 cured eyes and 42 improved eyes in the control group,and the effective rate was 81.67%.There were significant differences after statistics analysis(P<0.05). The Clinical symptoms and signs,Schirmer test(SIT),break up time(BUT) of tear film,corneal fluorescein staining ( FL) were obviously improved in the treatment group after treatmet, and it was better than the control gorup ( P <0.05 ) .Conclusion:The curative effect of the traditional Chinese medicine Qingxuan Runmu in on meibomian gland dys-function inducing the evaporative dry eyes is superior to that of Tobramycin and Dexamethasone eye drops.
