CAJ | 학술논문

目的：观察地佐辛复合罗哌卡因用于产妇硬膜外全产程分娩镇痛的疗效和安全性。方法选择自然分娩的年轻产妇400例，ASA l ~Ⅱ级，分为观察组（A 组）和对照组（B 组），每组200例，其中 A 组患者接受硬膜外100μg/ ml 地佐辛+0.1%罗哌卡因镇痛，B 组接受硬膜外0.1%罗哌卡因镇痛。记录两组产妇的疼痛程度（VAS 评分）、产程（第一、二、三产程）时间、新生儿 Apgar 评分、剖宫产率、器械助产及缩宫素使用情况。结果 A、B 两组VAS 疼痛评分在2、18 h 差异无统计学意义（P >0.05），在6、10、14 h 差异有统计学意义（P <0.05）；A 组第一产程短于 B 组，差异有统计学意义（P <0.05），两组在第二、第三产程差异无统计学意义（P >0.05）；A 组剖宫产率明显低于 B 组，两组差异有统计学意义（P <0.05）；新生儿娩出后1、5 min 的 Apgar 评分、器械助产率方面、缩宫素使用方面差异无统计学意义（P >0.05）。结论地佐辛复合罗哌卡因用于产妇硬膜外全产程分娩镇痛安全有效，缩短了第一产程且降低了剖宫产率，增加了母婴安全，值得推广。
목적：관찰지좌신복합라고잡인용우산부경막외전산정분면진통적료효화안전성。방법선택자연분면적년경산부400례，ASA l ~Ⅱ급，분위관찰조（A 조）화대조조（B 조），매조200례，기중 A 조환자접수경막외100μg/ ml 지좌신+0.1%라고잡인진통，B 조접수경막외0.1%라고잡인진통。기록량조산부적동통정도（VAS 평분）、산정（제일、이、삼산정）시간、신생인 Apgar 평분、부궁산솔、기계조산급축궁소사용정황。결과 A、B 량조VAS 동통평분재2、18 h 차이무통계학의의（P >0.05），재6、10、14 h 차이유통계학의의（P <0.05）；A 조제일산정단우 B 조，차이유통계학의의（P <0.05），량조재제이、제삼산정차이무통계학의의（P >0.05）；A 조부궁산솔명현저우 B 조，량조차이유통계학의의（P <0.05）；신생인면출후1、5 min 적 Apgar 평분、기계조산솔방면、축궁소사용방면차이무통계학의의（P >0.05）。결론지좌신복합라고잡인용우산부경막외전산정분면진통안전유효，축단료제일산정차강저료부궁산솔，증가료모영안전，치득추엄。
Objective:Objective To observe the effect and safety of dezocine - ropivacaine combination on the whole la-bor process of maternal epidural analgesia. Methods:To choose 400 cases of young mothers with natural childbirth,ASAⅠ ~ Ⅱ grade ,divided into two groups,observing group(A group )and comparison group( group B),200 cases in each group. Patients in A group received epidural 100 μg/ ml to the rank and file Sim + 0. 1 % ropivacaine analgesia,Patients in B group received epidural analgesia with ropivacaine 0. 1%. Record two maternal pain(VAS score),labor(first,sec-ond,third stage of labor)time,Apgar score,cesarean section rate,instrumental delivery and use of oxytocin. Results:A and B groups at 2,18h VAS pain scores showed no significant difference(P > 0. 05),at 6,10,14h difference was statisti-cally significant(P < 0. 05);production process of A group is shorter than B group,the difference was statistically signifi-cant(P < 0. 05),the difference was in the second and third stage of labor was not statistically significant(P > 0. 05);A group was significantly lower rate of cesarean section in group B,the difference was statistically significant(P < 0. 05);after neonates 1,5 min Apgar score ,instrumental delivery rate,the use of oxytocin hormone difference was not statistically significant(Pˊ> 0. 05). Conclusion:Dezocine - ropivacaine conbinarion for narernal epiDural analgesia on whole proDuc-rion process is safe anD effecrive ,shorrening rhe firsr srage of labor anD reDuce rhe cesarean secrion rare,increasing rhe narer-nal anD chilD safery,is worrhy of pronorion.