CAJ | 학술논문

目的：观察痛觉中枢敏感化对偏头痛患者脑血流动力学的影响。方法随机分为正常对照组、偏头痛组，应用 CA 症状自评量表，将偏头痛患者分为无 CA 组和 CA 组。应用美国 Ge ViVid e9超声诊断仪，对偏头痛患者发作后2h 进行脑血流动力学测定。结果在入组的108例患者中，偏头痛发病后2 h，72例患者出现 CA，出现率为66.7%，25、20、27人分别出现轻、中、重 CA，出现率分别为23.1%、18.5%、25.1%。72例偏头痛患者有 CA，36例患者无 CA。无 CA、CA 患者脑平均血流速度与正常对照组相比，血流速度显著增加，P <0.01；CA 患者与无 CA 患者相比，血流速度明显增加，P <0.01。结论偏头痛患者存在脑血流动力学异常，脑平均血流速度增加，在偏头痛中枢敏感化患者中更加显著。
목적：관찰통각중추민감화대편두통환자뇌혈류동역학적영향。방법수궤분위정상대조조、편두통조，응용 CA 증상자평량표，장편두통환자분위무 CA 조화 CA 조。응용미국 Ge ViVid e9초성진단의，대편두통환자발작후2h 진행뇌혈류동역학측정。결과재입조적108례환자중，편두통발병후2 h，72례환자출현 CA，출현솔위66.7%，25、20、27인분별출현경、중、중 CA，출현솔분별위23.1%、18.5%、25.1%。72례편두통환자유 CA，36례환자무 CA。무 CA、CA 환자뇌평균혈류속도여정상대조조상비，혈류속도현저증가，P <0.01；CA 환자여무 CA 환자상비，혈류속도명현증가，P <0.01。결론편두통환자존재뇌혈류동역학이상，뇌평균혈류속도증가，재편두통중추민감화환자중경가현저。
Objective:To explore the effect of pain central sensitization on migrainal patientsˊ cerebral haemedynamics. Method:The patients were randomly divided into control group and migraine group. The migrainal patients were divied into CA group and Not - have CA group using CA symptom checklist. The patientsˊcerebral haemedynamics 2 hours after the at-tack of migraine wered measured using American Ge ViVid e9 ultrosonic diagnostic equipment. Results:Among all the 108 patients,2 hours after the attack of migraine,CA emerges in 72 cases,the occurrence rate is 66. 7% ,25 cases are of slight CA degree,20 cases moderate degree and 27 cases severe degree,the occurrence rate is 23. 1% ,18. 5% and 25. 1% respectively. 72 cases have CA while 36 cases donˊt have. Comapred with control group,the average cerebral blood speed of not - have CA,CA patients increases significantly,p < 0. 01;Comapred with not - have CA patients,the blood speed of CA patients increases sharply,p < 0. 01. Conclusion:Cerebral haemedynamics abnormality exists in migrainal pq-tients,and the average cerebral blood speed increases,which is more significant in central sensitization of migraine.