泰山医学院学报
泰山醫學院學報
태산의학원학보
JOURNAL OF TAISHAN MEDICAL COLLEGE
2014年
9期
902-903
,共2页
高血压%左室肥厚%奥美沙坦酯
高血壓%左室肥厚%奧美沙坦酯
고혈압%좌실비후%오미사탄지
hypertension%left ventricular hypertrophy%olmesartan medoxomil
目的:评价服用奥美沙坦逆转高血压病左室肥厚的疗效。方法选择门诊高血压病伴左室肥厚患者56例,给予奥美沙坦酯片治疗,4周后评价患者左室舒张末期内径(LVDd),舒张期室间隔厚度(IVSd)、左室后壁厚度(LVPWd)及左室重量指数(LVMI)变化,并观察其对患者血尿常规、肝肾功能、血脂、血糖的影响。结果4周后共50例患者收缩压及舒张压均降至正常;治疗后患者 IVSd、LVPWd 及 LVMI 均较治疗前明显下降( P <0.05),而LVDd 无明显变化;治疗后对血尿常规、肝肾功能、血脂、血糖无影响。结论高血压病伴左室肥厚患者每天服用奥美沙坦酯20~40 mg 能有效地逆转左室肥厚。
目的:評價服用奧美沙坦逆轉高血壓病左室肥厚的療效。方法選擇門診高血壓病伴左室肥厚患者56例,給予奧美沙坦酯片治療,4週後評價患者左室舒張末期內徑(LVDd),舒張期室間隔厚度(IVSd)、左室後壁厚度(LVPWd)及左室重量指數(LVMI)變化,併觀察其對患者血尿常規、肝腎功能、血脂、血糖的影響。結果4週後共50例患者收縮壓及舒張壓均降至正常;治療後患者 IVSd、LVPWd 及 LVMI 均較治療前明顯下降( P <0.05),而LVDd 無明顯變化;治療後對血尿常規、肝腎功能、血脂、血糖無影響。結論高血壓病伴左室肥厚患者每天服用奧美沙坦酯20~40 mg 能有效地逆轉左室肥厚。
목적:평개복용오미사탄역전고혈압병좌실비후적료효。방법선택문진고혈압병반좌실비후환자56례,급여오미사탄지편치료,4주후평개환자좌실서장말기내경(LVDd),서장기실간격후도(IVSd)、좌실후벽후도(LVPWd)급좌실중량지수(LVMI)변화,병관찰기대환자혈뇨상규、간신공능、혈지、혈당적영향。결과4주후공50례환자수축압급서장압균강지정상;치료후환자 IVSd、LVPWd 급 LVMI 균교치료전명현하강( P <0.05),이LVDd 무명현변화;치료후대혈뇨상규、간신공능、혈지、혈당무영향。결론고혈압병반좌실비후환자매천복용오미사탄지20~40 mg 능유효지역전좌실비후。
ObJective:To evaluate the efficacy of taking olmesartan for reversal in patients with essential hypertension. Methods:Hypertension patients with LVH were given olmesartan medoxomil. The left ventricular end diastolic diameter (LVDd),interventricular septal thickness(IVSd),left ventricular posterior wall thickness(LVPWd)and left ventricular mass index(LVMI)changes were evaluated after 4 weeks of treatment. The blood and urine routine,hepatic and renal function,blood lipid,blood glucose of patients were also observed. Results:After 4 weeks,the blood pressure of the 50 patients decreased to normal;The IVSd,LVPWd and LVMI were significantly decreased than those before treatment(P <0. 05),while LVDd had no obvious change;The blood and urine routine,blood lipid,blood glucose,liver and kidney function were not changed. Conclusion:Taking olmesartan medoxomil 20 ~ 40 Mg can effectively reverse the left ventricular hypertrophy in patients with left ventricular hypertrophy.