针灸临床杂志
針灸臨床雜誌
침구림상잡지
JOURNAL OF CLINICAL ACUPUNCTURE AND MOXIBUSTION
2014年
10期
56-62,63
,共8页
张红丽%张虹%朱原%傅立新%刘志顺
張紅麗%張虹%硃原%傅立新%劉誌順
장홍려%장홍%주원%부립신%류지순
便秘%针灸%药物%系统评价
便祕%針灸%藥物%繫統評價
편비%침구%약물%계통평개
Constipation%Acupuncture%Drug%Systematic evaluation
评价针灸与药物对照治疗单纯性功能性便秘的优效性。按照循证医学的要求全面检索关于针灸治疗单纯性功能性便秘的国内外文献,选择符合要求的随机对照试验( RCT)和临床对照试验( CCT)进行系统评价,并使用专门的统计学软件对其进行Meta分析。结果显示针灸无论是近期有效率、愈显率(包括治疗前后的自主排便次数、CCS、症状量表评分比较方面),还是远期有效率,均不亚于药物组,且随访复发率低,安全性均良好。另腹部天枢深刺电针组在CCS评分方面优于药物组,但在改善自主排便方面与药物组疗效相当。而天枢常规刺电针与药物组在CCS评分方面效果无明显差别。但因所纳文献少,敏感性分析较大,存在发表偏倚,且大多量表指标未给予差值分析,导致Meta分析有一定的困难,故尚需较大样本的多中心对照试验和进一步的临床规范化指标予以证实。
評價針灸與藥物對照治療單純性功能性便祕的優效性。按照循證醫學的要求全麵檢索關于針灸治療單純性功能性便祕的國內外文獻,選擇符閤要求的隨機對照試驗( RCT)和臨床對照試驗( CCT)進行繫統評價,併使用專門的統計學軟件對其進行Meta分析。結果顯示針灸無論是近期有效率、愈顯率(包括治療前後的自主排便次數、CCS、癥狀量錶評分比較方麵),還是遠期有效率,均不亞于藥物組,且隨訪複髮率低,安全性均良好。另腹部天樞深刺電針組在CCS評分方麵優于藥物組,但在改善自主排便方麵與藥物組療效相噹。而天樞常規刺電針與藥物組在CCS評分方麵效果無明顯差彆。但因所納文獻少,敏感性分析較大,存在髮錶偏倚,且大多量錶指標未給予差值分析,導緻Meta分析有一定的睏難,故尚需較大樣本的多中心對照試驗和進一步的臨床規範化指標予以證實。
평개침구여약물대조치료단순성공능성편비적우효성。안조순증의학적요구전면검색관우침구치료단순성공능성편비적국내외문헌,선택부합요구적수궤대조시험( RCT)화림상대조시험( CCT)진행계통평개,병사용전문적통계학연건대기진행Meta분석。결과현시침구무론시근기유효솔、유현솔(포괄치료전후적자주배편차수、CCS、증상량표평분비교방면),환시원기유효솔,균불아우약물조,차수방복발솔저,안전성균량호。령복부천추심자전침조재CCS평분방면우우약물조,단재개선자주배편방면여약물조료효상당。이천추상규자전침여약물조재CCS평분방면효과무명현차별。단인소납문헌소,민감성분석교대,존재발표편의,차대다량표지표미급여차치분석,도치Meta분석유일정적곤난,고상수교대양본적다중심대조시험화진일보적림상규범화지표여이증실。
Evaluate the effect of acupuncture and drug control for the treatment for simple functional constipa-tion.According to the requirements of Evidence-based medicine, we research domestic and foreign literature overall about acupuncture treatment for simple functional constipation, and choose the qualified randomized con-trolled trial ( RCT) and controlled clinical trials ( CCT) for the systematic evaluation, and use special statistical software for Meta-analysis.The results show that acupuncture is not inferior to the drug control group both in the recent effective rate,the markedly effective rate, including improving the symptoms of independent stool fre-quency, CCS and symptoms scale, and in the forward efficient, what is more, it is safe and the follow-up re-currence rate is low.The deep acupuncture method at Tianshu (ST 25) in improving the CCS is superior to the drug control group, but has the equivalent efficacy in the independent defecation.And the effect of routine acu-puncture method at Tianshu ( ST 25 ) in improving the CCS is similar compared with drug control group.But due to the less literature, sensitivity analysis, publication bias exists, and there is no difference analysis on most rating scales.Meta analysis has some difficulty,and it remains to be a larger sample of multicenter con-trolled trial and further standardization of clinical indicators.