CAJ | 학술논문

目的：探讨围生期先天性心脏病( congenital heart disease, CHD)的发生情况,为制定干预措施提供依据。方法选取2011年1月-2013年12月咸阳市两家市级医院引产或分娩的24757例围生儿CHD筛查情况进行分析。结果共筛查出CHD 496例。围生期CHD发生率及超声心动图检查率呈逐年上升趋势。 CHD分类前3位依次为动脉导管未闭(42.94%)、室间隔缺损(20.36%)、房间隔缺损(14.52%)；复合CHD共104例(20.97%),以房间隔缺损合并室间隔缺损(4.64%)及法洛四联症(2.42%)居多,其中复杂CHD 57例(11.49%)。21例还合并其他先天畸形。随孕母年龄的增加,围生期CHD的发生率呈上升趋势,尤其孕母年龄<20岁及≥35岁CHD的发生率最高。结论加强围生期CHD监测并制定干预措施,对提高出生人口素质具有重要意义。
목적：탐토위생기선천성심장병( congenital heart disease, CHD)적발생정황,위제정간예조시제공의거。방법선취2011년1월-2013년12월함양시량가시급의원인산혹분면적24757례위생인CHD사사정황진행분석。결과공사사출CHD 496례。위생기CHD발생솔급초성심동도검사솔정축년상승추세。 CHD분류전3위의차위동맥도관미폐(42.94%)、실간격결손(20.36%)、방간격결손(14.52%)；복합CHD공104례(20.97%),이방간격결손합병실간격결손(4.64%)급법락사련증(2.42%)거다,기중복잡CHD 57례(11.49%)。21례환합병기타선천기형。수잉모년령적증가,위생기CHD적발생솔정상승추세,우기잉모년령<20세급≥35세CHD적발생솔최고。결론가강위생기CHD감측병제정간예조시,대제고출생인구소질구유중요의의。
Objective To explore the incidence of perinatal congenital heart disease ( CHD) , so as to provide scien-tific evidence of intervention measures. Methods A total of 24 757 cases in two city level hospitals of Xianyang between Jan-uary 2011 and December 2013 were selected to statistically analyze the incidence of perinatal CHD. Results There were 496 cases of CHD and there was an increasing trend year by year in both the incidence of perinatal CHD and the examination rate of ultrasonic cardiogram. The top three CHD classified types in order were patent ductus arteriosus (42. 94%), ventricular septal defect (20. 36%) and atrial septal defect (14. 52%). There were 57 cases of complex CHD (11. 49%) in 104 cases of composite CHD (20. 97%). Infants with atrial septal defect complicated by ventricular septal defect(4. 64%) and tetralogy of fallot(2. 42%) were major types in composite CHD cases. There were 21 cases of CHD associated with other congenital malformations. The incidence of perinatal CHD increased with the age of pregnant women, especially less than 20 years old and greater than or equal to 30 years of age. Conclusion Strengthening the surveillance of perinatal CHD and formulating in-tervention measures for the region can be great significant to reduce the incidence of CHD and other birth defects and improve the quality of birth population.