中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2014年
5期
874-875
,共2页
更年期抑郁%米氮平%坤泰胶囊%躯体化症状
更年期抑鬱%米氮平%坤泰膠囊%軀體化癥狀
경년기억욱%미담평%곤태효낭%구체화증상
menopauseal depression%mirtazapine%kuntai capsule%somatization symtom
目的:探讨米氮平联合坤泰胶囊对更年期抑郁症的疗效。方法将54例符合更年期首发抑郁障碍的患者随机分成米氮平联合坤泰胶囊治疗组(观察组)和单用米氮平治疗组(对照组),疗程8周。采用汉密尔顿抑郁量表( HAMD)评定疗效。结果治疗2、4、6、8周后观察组的HAMD评分显著低于对照组,两组HAMD评分比较均有显著性差异( t值分别为2.46、4.78、4.98、6.22,均P<0.05)。两组躯体化症状在治疗后1、2、4、6、8周比较均有显著性差异(t值分别为1.11、2.79、2.86、3.01、3.11,均P<0.01)。结论米氮平联合坤泰胶囊治疗更年期抑郁症起效快、效果好。
目的:探討米氮平聯閤坤泰膠囊對更年期抑鬱癥的療效。方法將54例符閤更年期首髮抑鬱障礙的患者隨機分成米氮平聯閤坤泰膠囊治療組(觀察組)和單用米氮平治療組(對照組),療程8週。採用漢密爾頓抑鬱量錶( HAMD)評定療效。結果治療2、4、6、8週後觀察組的HAMD評分顯著低于對照組,兩組HAMD評分比較均有顯著性差異( t值分彆為2.46、4.78、4.98、6.22,均P<0.05)。兩組軀體化癥狀在治療後1、2、4、6、8週比較均有顯著性差異(t值分彆為1.11、2.79、2.86、3.01、3.11,均P<0.01)。結論米氮平聯閤坤泰膠囊治療更年期抑鬱癥起效快、效果好。
목적:탐토미담평연합곤태효낭대경년기억욱증적료효。방법장54례부합경년기수발억욱장애적환자수궤분성미담평연합곤태효낭치료조(관찰조)화단용미담평치료조(대조조),료정8주。채용한밀이돈억욱량표( HAMD)평정료효。결과치료2、4、6、8주후관찰조적HAMD평분현저저우대조조,량조HAMD평분비교균유현저성차이( t치분별위2.46、4.78、4.98、6.22,균P<0.05)。량조구체화증상재치료후1、2、4、6、8주비교균유현저성차이(t치분별위1.11、2.79、2.86、3.01、3.11,균P<0.01)。결론미담평연합곤태효낭치료경년기억욱증기효쾌、효과호。
Objective To explore the curative effect of mirtazapine combined with kuntai capsule on menopausal depression.Methods Fifty-four patients with menopausal depression were recruited in the study, and they were randomly divided into two groups: mirtazapine combined with kuntai capsule group ( observation group) and single mirtazapine group ( control group) .The treatment course was 8 weeks. The efficacy was assessed with Hamilton depression scale (HAMD).Results HAMD scores of the observation group were significantly lower than those of the control group after treatment for 2, 4, 6 and 8 weeks (t value was 2.46, 4.78, 4.98 and 6.22, respectively, all P<0.05).The differences in somatization symptoms were significant between two groups after treatment for 1, 2, 4, 6 and 8 weeks (t value was 1.11, 2.79, 2.86, 3.01 and 3.11, respectively, all P<0.01).Conclusion In the treatment of menopausal depression, mirtazapine combined with kuntai capsule is effective with fast action.