CAJ | 학술논문

目的：探讨小儿呼吸道肺炎支原体（ MP）感染与家庭密切接触者的相关性。方法对2012年1月1日至2012年12月31日期间在晋江市医院晋南分院儿科就诊的MP免疫球蛋白M（ MPIgM）检测阳性的急性呼吸道感染患儿220例，家庭中密切接触者220人，进行MP免疫球蛋白G（MPIgG）、MPIgM检测。结果 MPIgM检测阳性42例，阳性率为19．1％；MPIgG定量检测＞16的126例，阳性率为57．3％；MPIgM或MPIgG检测1项阳性的共140例，总阳性率为63．6％。 MPIgM和MPIgG均阳性组患儿中，病程61～90d者的比例为43．10％，高于单MPIgG阳性组（28．57％）及单MPIgM阳性组的14．29％，差异均具有统计学意义（χ2值分别为3．452、3．148，均P＜0．05）。 MPIgM和MPIgG均阳性组的复发频率为≥3次的比例高于MPIgM阳性组以及MPIgG阳性组，差异均具有统计学意义（χ2值分别为3．452、3．148，均P＜0．05）。结论小儿MP感染与家庭密切接触者MP隐性感染具有密切的相关性，双亲MP隐性感染的患儿其发病率较高、病程较长、病情复发频率较高，肺外合并症发生较高，因此应加强对该类患儿的防治，以减少MP患儿的发生。
목적：탐토소인호흡도폐염지원체（ MP）감염여가정밀절접촉자적상관성。방법대2012년1월1일지2012년12월31일기간재진강시의원진남분원인과취진적MP면역구단백M（ MPIgM）검측양성적급성호흡도감염환인220례，가정중밀절접촉자220인，진행MP면역구단백G（MPIgG）、MPIgM검측。결과 MPIgM검측양성42례，양성솔위19．1％；MPIgG정량검측＞16적126례，양성솔위57．3％；MPIgM혹MPIgG검측1항양성적공140례，총양성솔위63．6％。 MPIgM화MPIgG균양성조환인중，병정61～90d자적비례위43．10％，고우단MPIgG양성조（28．57％）급단MPIgM양성조적14．29％，차이균구유통계학의의（χ2치분별위3．452、3．148，균P＜0．05）。 MPIgM화MPIgG균양성조적복발빈솔위≥3차적비례고우MPIgM양성조이급MPIgG양성조，차이균구유통계학의의（χ2치분별위3．452、3．148，균P＜0．05）。결론소인MP감염여가정밀절접촉자MP은성감염구유밀절적상관성，쌍친MP은성감염적환인기발병솔교고、병정교장、병정복발빈솔교고，폐외합병증발생교고，인차응가강대해류환인적방치，이감소MP환인적발생。
Objective To investigate the correlation between pediatric respiratory Mycoplasma pneumoniae ( MP ) infection and close household contacts.Methods From January 1 to December 31 in 2012,220 children with acute respiratory infection were detected with positive MPIgM in pediatrics department of Jinnan Branch of Jinjiang City Hospital.Enzyme-linked immunosorbent assay was used to detect MPIgG and IgM for them and 220 close household contacts.Results MPIgM test was positive in 42 cases, and the positive rate was 19.1%.Quantitative detection of MPIgG>16 were found in 126 cases, and the positive rate was 57.3%.There were 140 cases with positive results in either MPIgM or MPIgG testing, with a total positive rate of 63.6%.Among children with both positive MPIgM and MPIgG, 43.10%had a course of 61 to 90d, which was higher than the proportion of MPIgG positive group (28.57%) and MPIgM positive group (14.29%) , and the differences were significant (χ2 value was 3.452 and 3.148, respectively, both P<0.05) .The proportion of MPIgM and MPIgG positive group with recurrence frequency≥3 times was significantly higher than that of MPIgM positive group and MPIgG positive group (χ2 value was 3.452 and 3.148, respectively, both P<0.05).Conclusion MP infection in children is closely related with close household contacts with MP latent infection.The incidence of MP infection in children whose parents with MP latent infection is relatively high, and their disease course is long and recurrent frequency is high.The incidence of pulmonary complications is high, so prevention and treatment of children should be strengthened to reduce the incidence of children MP.