CAJ | 학술논문

目的：研究超声监测子痫前期血流改变特点及与围生儿预后的关系。方法选取2010年1月至2014年1月浙江省丽水市中心医院收治的100例子痫前期孕妇，依据病情严重程度将这些孕妇分为轻度子痫前期组（ A组）和重度子痫前期组（ B组）两组，每组50例。依据血流动力学分型标准将这些患者分为正常排阻型组（ T1组）、正常排高阻型组（ T2组）、低排高阻型组（ T3组）、高排低阻型组（ T4组）4组，每组25例。另选取同期住院的50例孕妇作为对照组，运用妊娠高血压疾病监测系统（ Mp）进行测试。结果 A组孕妇的平均动脉压、外周阻力均明显比对照组高（t值分别为4．303、2．571，均P＜0．05），B组孕妇的平均动脉压、K值、外周阻力、血液粘度均明显比对照组高（t值分别为4．303、2．776、2．571、3．078，均P＜0．05），A组患者的平均动脉压、K值、外周阻力、血液滞留时间、血液粘度均明显高于B组（t值分别为4．303、2．776、2．571、3．078，均P＜0．05）。 T3组围生儿小于胎龄儿（SGA）、新生儿窒息发生率均较其他各组显著升高（t值分别为7．38、7．81，均P＜0．05），T4组早产、死胎、死产发生率较其他各组显著升高（t值分别为9．38、5．99，均P＜0．05）。结论超声监测子痫前期患者的血流改变，能显著提升围生儿SGA和死胎死产的诊出率，便于临床早期干预。
목적：연구초성감측자간전기혈류개변특점급여위생인예후적관계。방법선취2010년1월지2014년1월절강성려수시중심의원수치적100례자간전기잉부，의거병정엄중정도장저사잉부분위경도자간전기조（ A조）화중도자간전기조（ B조）량조，매조50례。의거혈류동역학분형표준장저사환자분위정상배조형조（ T1조）、정상배고조형조（ T2조）、저배고조형조（ T3조）、고배저조형조（ T4조）4조，매조25례。령선취동기주원적50례잉부작위대조조，운용임신고혈압질병감측계통（ Mp）진행측시。결과 A조잉부적평균동맥압、외주조력균명현비대조조고（t치분별위4．303、2．571，균P＜0．05），B조잉부적평균동맥압、K치、외주조력、혈액점도균명현비대조조고（t치분별위4．303、2．776、2．571、3．078，균P＜0．05），A조환자적평균동맥압、K치、외주조력、혈액체류시간、혈액점도균명현고우B조（t치분별위4．303、2．776、2．571、3．078，균P＜0．05）。 T3조위생인소우태령인（SGA）、신생인질식발생솔균교기타각조현저승고（t치분별위7．38、7．81，균P＜0．05），T4조조산、사태、사산발생솔교기타각조현저승고（t치분별위9．38、5．99，균P＜0．05）。결론초성감측자간전기환자적혈류개변，능현저제승위생인SGA화사태사산적진출솔，편우림상조기간예。
Objective To study the characteristics of blood flow changes of preeclampsia under ultrasound monitoring and its relationship with the prognosis of perinatal infants.Methods From January 2010 to January 2014 100 cases of pregnant women with preeclampsia in Lishui Central Hospital were selected, and they were divided into two groups according to severity of disease: mild preeclampsia group ( group A) and severe preeclampsia group ( group B) with 50 cases in each group.These patients were also divided into four groups, normal group (T1 group), normal discharge high resistance group (T2 group), low discharge high resistance group (T3 group), high discharge low resistance group ( T4 group) , according to hemodynamic classification criteria with 25 cases in each group.Another 50 cases of pregnant women admitted in the same period in the hospital were selected as the control group.Pregnancy-induced hypertension monitoring system ( Mp) was used for testing.Results The mean arterial pressure and peripheral resistance of group A were significantly higher than the control group (t value was 4.303 and 2.571, respectively, both P<0.05), and the mean arterial pressure, K value, peripheral resistance and blood viscosity of group B were significantly higher than those of the control group ( t value was 4.303, 2.776, 2.571, 2.447 and 3.078, respectively, all P<0.05).The incidences of small for gestational age (SGA) infants and neonatal asphyxia in T3 group were significantly higher than other groups (t value was 7.38 and 7.81, respectively, both P<0.05), and the incidences of premature delivery and dead birth in T4 group were significantly higher than other groups (t value was 9.38 and 5.99, respectively, both P<0.05).Conclusion Ultrasound monitoring blood flow changes of preeclampsia can significantly enhance the detection rates of perinatal SGA and stillbirths, and make it convenient for early intervention in clinics.