CAJ | 학술논문

患者1年前吞入刀片，在我院行剖腹探查术，术中见肠管破裂穿孔，行“结肠异物取出术+部分小肠、结肠切除术”。术后抗感染治疗4天后自动出院。出院后发热，患者再次入住普外科。腹腔脓液、分泌物培养示大肠埃希菌、肺炎克雷伯菌、粪肠球菌、奇异变形杆菌以及星座链球菌等多种细菌，患者所用药物疗效不佳，临床药师先后两次参加会诊，根据药敏结果和患者病情，建议改用美罗培南联合万古霉素抗感染，临床采纳。治疗期间，药师关注患者用药后各项指标变化。经治疗，患者体温、血常规、C 反应蛋白等感染指标逐渐恢复正常，病情得到控制。
환자1년전탄입도편，재아원행부복탐사술，술중견장관파렬천공，행“결장이물취출술+부분소장、결장절제술”。술후항감염치료4천후자동출원。출원후발열，환자재차입주보외과。복강농액、분비물배양시대장애희균、폐염극뢰백균、분장구균、기이변형간균이급성좌련구균등다충세균，환자소용약물료효불가，림상약사선후량차삼가회진，근거약민결과화환자병정，건의개용미라배남연합만고매소항감염，림상채납。치료기간，약사관주환자용약후각항지표변화。경치료，환자체온、혈상규、C 반응단백등감염지표축점회복정상，병정득도공제。
One 32-year male patient was admitted to our hospital because of abdominal pain for eight days and intestinal perforation rupture after five days. The patient swallowed a blade one year ago. He un-derwent laparotomy on 09-13 and took colectomy for ruptured bowel perforation. He admitted anti-infection treatment for 4 days and left the hospital. After discharge, the patient got a fever and came back on 09-19. The culture of abdominal pus and secretions showed escherichia coli, klebsiella pneumoniae, enterococ-cus faecalis, proteus mirabilis and streptococcus constellatus. The clinical pharmacists gave pharmacy con-sultation two times, advising the doctor to give the patient meropenem combined with vancomycin for thera-py according to the bacterial culture. The pharmacists gave the patient pharmaceutical care based on the changes of the infectious indicators. After the therapy, the patient's body temperature, blood test and C-re-active protein gradually returned to normal. These indicated that the infection became under control.